Studies on the Antimicrobial Activity of Juglans regia

Abstract

Juglans regia L. bark is used in some countries as a toothbrush and as a dye for coloring the lips for cosmetic purposes. Its extract showed a broad spectrum antimicrobial activity in a dose dependent manner. It inhibited the growth of several species of pathogenic micro-organisms representing Gram-positive bacteria (Staphylococcus aureus and Streptococcus mutans), Gram-negative bacteria (Esherichia coli and Pseudomonas aeruginosa) and a pathogenic yeast (Candida albicans). The extract has either synergistic or additive action when tested with a wide range of antibacterial drugs. It also increased the pH of saliva. Thus, brushing the teeth with this bark may improve oral hygiene, prevent plaque and caries formation, and reduce the incidence of gingival and periodontal infections.

Antibacterial Effect of Juglans Regia Bark against Oral Pathologic Bacteria

“…Many parts of Green walnuts such as shells, kernel and seed, bark, and leaves are used in the pharmaceutical and beauty industry [6, 7]. Juglans regia L. bark is used in some countries as a toothbrush and as a dye for coloring the lips for makeup purpose [8]. Walnut (Juglans regia L.) bark has been claimed to own anti-inflammatory, blood purify, anticancer, depurative, diuretic, and laxative activities.…”

Hepatoprotective effects of Juglans regia extract against CCl4-induced oxidative damage in rats

“…Leaves are easily available and in abundant amounts, while tree bark is scarce and its collection compromise the plant life. Walnut leaves are considered a source of healthcare compounds, and have been widely used in traditional medicine for he treatment of skin inflammation, venous insufficiency, hyperhidrosis haemorrhoidal symptomatology and ulcers, and for its antidiarrheic, antihelmintic, depurative, antiseptic, antibacterial, astringent, antioxidants and chemopreventive properties (Alkhawajah, 1997;Bruneton, 1993Bruneton, , 1999Carvalho et al, 2010;Van Hellemont, 1986;Wichtl & Anton, 1999). Keratolytic, antifungal, hypoglycaemic, hypotensive, anti-scrofulous and sedative activities have also been described (Gîrzu et al, 1998;Valnet, 1992).…”

Total phenols, antioxidant potential and antimicrobial activity of walnut (Juglans regia L.) green husks

“…Studies have also demonstrated the antimicrobial activity of walnut products, particularly of bark (Alkhawajah, 1997), leaves (Clark et al, 1990;Pereira et al, 2007b), fruits and the specific compound juglone (Clark et al, 1990) but until this time the information about walnut green husks is almost inexistent.…”