Studies on the constituents of asclepiadaceae plants. LVI. Isolation of new antitumor-active glycosides from Dregea volubilis (L.) Benth.

Yoshimura, Seiji; Narita, Hiromi; Hayashi, Kôji; Mitsuhashi, Hiroshi

doi:10.1248/cpb.31.3971

Cited by 66 publications

(48 citation statements)

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“…The leaves and flowers are used as vegetables. Drevogenin D and kaempferol have been isolated from the leaves, whereas dregeosides, hyperoside, drevogenin A and P, drebbysogenin were isolated from its seed, stem, and root (Anon, 1976;Yoshimura et al, 1983Yoshimura et al, , 1985. Sahu et al (2002) isolated volubilioside A, B, C and drevogenin D and P from its flowers.…”

Section: Research Articlementioning

confidence: 99%

“…Sahu et al (2002) isolated volubilioside A, B, C and drevogenin D and P from its flowers. Dregeoside A p1 and dregeoside A 01 , isolated from stem of the plant, showed antitumor activity against melanoma B-16 (Yoshimura et al, 1983). Taraxerone isolated from chloroform extract of the fruit of the plant show in vitro antitumor and antileishmanial activity (Moulisha et al, 2009(Moulisha et al, , 2010.…”

Section: Research Articlementioning

confidence: 99%

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In vitroandin vivoantitumor activity of a methanol extract ofDregea volubilisleaves with its antioxidant effect

Hossain¹,

Chakroborty

Milan

et al. 2012

Pharmaceutical Biology

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Section: Research Articlementioning

confidence: 99%

Section: Research Articlementioning

confidence: 99%

In vitroandin vivoantitumor activity of a methanol extract ofDregea volubilisleaves with its antioxidant effect

Hossain¹,

Chakroborty

Milan

et al. 2012

Pharmaceutical Biology

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“…W. volubilis Leaf paste is removed along with pepper to treat dyspepsia (Pandikumar, et al, 2007). Bark paste, mixed with hot milk is utilized internally for treating urinary troubles (Silija et al, 2008), and leaf powder is taken orally along with cow's milk have antidiabetic activity (Ayyanar et al, 2008) The literature survey revealed that among the various saponins obtained from the stem and flower of W. volubilis, two compounds are active against Ehrlich's as cites carcinoma (Yoshimura, et al, 1983 andSahu, et al, 2002). Since W. volubilis has been reported to possess medicinal effects, the anti-inflammatory, analgesic and anti-pyretic activities exhibited by the constituents present in the dried root ethanol extract.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical screening, FT-IR analysis and antimicrobial activity of Wattakaka volubilis

Selvaraj¹,

Anithakumari²,

Balamurugan³

et al. 2016

IJBR

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The present study was evaluated the phytochemical analysis and antibacterial activity of Wattakaka volubilis leaf extract. The Wattakaka volubilis is medicinal plant used in the treatment of various diseases (Wound, diabetics, rheumatic and diarrhea). The ethanol, methanol, petroleum ether and DMSO extract from the leaf of Wattakaka volubilis were screened on their phytochemicals analysis. Among thesePhytochemicals were alkaloids, anthroquione, caumarin, flavanoids, phenols, saponins, steroids, tannins and terpenoids for present in the following extracts ethanol, methanol. The petroleum ether and DMSO only present in several phytochemicals like alkaloid, anthroquinone, terpenoids and tannins. Wattakaka volubilis against the antibacterial like E. coli, B. pumilus, Enterobacter aerogens, and Pseudomonas aeruginosa. The zone of inhibition of Wattkaka voulubilis leaf extract against the bacteria was maximum inhibition Pseudomonas aeruginosa, Enterobacter aerogens, Bacillus pumilis. The least zone of inhibition was recorded against E.coli. The characterization of the plant extract and the functional groups was analyzed in Fourier Transform Infrared Spectroscopy (FTIR). The absorbance bands analysis were observed in the region of 4000-400cm-1 are 23 compounds derived. The compounds represented the ranges from 3905.21 to 436.41 peaks were shown. This study which is the primary report on the phytochemicals analysis and antibacterial properties of Wattakaka volubilis supports its traditional uses in the treatment of infectious and non-infectious diseases.

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“…The juice of the leaves was found effective in treatment of experimentally induced diabetes in rats (Shetty et al, 1997). The plant showed anti-fibritic potential due to presence of pregnane and steroidal derivatives (Yoshimura et al, 1983). The aqueous extract of the leaves were found to be hepatotoxic in rats (Tennekoon et al, 1991).…”

Section: Introductionmentioning

confidence: 99%

Assessment of lactogenic potential of some traditional herbs

Raval¹,

Patel²,

Mishra³

2010

Oriental Pharmacy and Experimental Medicine

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SUMMARYThe entire plant of Leptadenia reticulata (Asclepidaceae) is extensively used as lactogen, traditionally, in veterinary practice. The plants of Dregea volubilis and Pentatropis microphylla (Asclepidaceae) are now used as its substitute and sometimes replace the original drug as traditional lactogen. The lactogenic potential of these drugs was studied in rats using, pup weight, weight of mother, parenchyma percentage, secretary rating, estimation of total protein content and glycogen content of mammary glands tissues as assessment parameters. HPTLC profiles of bioactive extracts were also generated to serve the authentification needs. The results of present studies show that P.microphylla forms a better substitute over D. volubilis.

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Studies on the constituents of asclepiadaceae plants. LVI. Isolation of new antitumor-active glycosides from Dregea volubilis (L.) Benth.

Cited by 66 publications

References 0 publications

In vitroandin vivoantitumor activity of a methanol extract ofDregea volubilisleaves with its antioxidant effect

In vitroandin vivoantitumor activity of a methanol extract ofDregea volubilisleaves with its antioxidant effect

Phytochemical screening, FT-IR analysis and antimicrobial activity of Wattakaka volubilis

Assessment of lactogenic potential of some traditional herbs

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