Studies on the Effect of Calcium‐, Strontium‐ and Barium‐Chloride on the Oxydation Processes in Various Tissues¹

Abstract

(With 1 4 tlgores in the text.)Among the ions affecting the physiological oxidation processes, those of Ca have attracted considerable attention ever since Thunberg's (1) pioneer micro-respirometer experiments twenty-five years ago. As the methods of studying tissue oxidation have been developed, a rather large number of studies upon the Ca effect have been published. Nevertheless, a more comprehensive investigation about the response of various tissues to the addition of Ca ions in various concentrations seems to be lacking. The present study tries to fill this gap, in that a large number of experiments have been carried out upon a number of tissues, both by the Warburg micro-respirometer method and by the Thunberg methylene blue technique.In addition, a comparative study has been performed on the effects of the earthly alkaline ions closely related to Ca, namely Sr and Ba.Also, the question of a possible antagonism between Ca and K has been subjected to renewed experimental procedures. Finally, a few preliminary experiments have been carried out upon the Ca effect upon certain enzyme systems which are involved in the tissue oxidation processes. Previous investigations.