Studies on the Function of the Kurloff Cell

Proteoglycans from sheep, pig, rat and human spleens having chemical and biological resemblances to that in Kurloff cells

“…In addition infrared bands absorbing at 805 cm-' and 1260 cm-' were observed in each case as well as those bands at 720 cm-', 850 cm-' and 928 cm-' swelling of macrophages followed in some cases by complete disruption of the cells. This phenomenon was similar to that first observed with the purified proteoglycan from guinea-pig spleens [7]. The majority of swollen cells were unable to exclude eosin when this was added to cultures as a test of cell viability, except for cells showing only the early signs of damage.…”

“…at a concentration of 1 pg/ml using the cells of peritoneal exudates of guinea-pigs as described [7].…”

Biology and Diseases of Guinea Pigs

“…The historical mean white count was considerably higher, suggesting that underlying subclinical disease may have contributed to a relative anemia and leukocytosis. Large numbers are seen also in the placenta, where they may have a role in preventing the maternal rejection of the fetal placenta during pregnancy (Marshall et al, 1971). Lymphocytes are the predominant leukocyte in the peripheral blood.…”

Hematological Assessment in Pet Guinea Pigs (Cavia porcellus)

“…2,17 The exact origin and function of these cells is unknown, although it has been speculated that they may function as natural killer cells in the general circulation or as protectors of fetal antigen in the placenta because their numbers can increase under the influence of increased estrogens. 8,13,17,19,[28][29][30][31] …”