Studies on the interactions between bile salts and food emulsifiers under in vitro duodenal digestion conditions to evaluate their bile salt binding potential

Abstract

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Dietary Emulsifiers Alter Composition and Activity of the Human Gut Microbiota in vitro, Irrespective of Chemical or Natural Emulsifier Origin

“…These compounds may thus readily reach the colon and interact with the endogenous microbiota. Fourth, other dietary constituents in the gut, primarily lipids, and bile salts, will interact with emulsifiers (Naso et al, 2019). The mucus layer overlying the gut epithelium and the pH-fluctuations throughout the gut are other elements that may affect emulsifier-microbiota interactions.…”

Bile salts in digestion and transport of lipids

“…Recent work has also studied interactions between BLG and BE, by combining transmission DL" -potential and conductivity measurements [75]. The bile aggregates that form upon an excess in BE concentration, evolve to a different supramolecular structure in the presence of low protein concentration, and eventually dissociate in the presence of high protein concentration.…”

Conversion of bile salts from inferior emulsifier to efficient smart emulsifier assisted by negatively charged nanoparticles at low concentrations

“… 18–22 On the one hand, BS tend to adsorb at the interface and replace other adsorbed surfactant or emulsifier molecules already present. 11,19 Although some recent studies focus on the interaction of BS with other emulsifiers or proteins at the interface, 23–27 studies dealing with BS as a unique emulsifier are very limited. On the other hand, some BS were observed to desorb from the interface at low concentrations.…”