Studies on the use of a formic acid‐propionic acid mixture (Bio‐add™) to control experimentalSalmonellainfection in broiler chickens

The use of organic acids to combatSalmonellain poultry: a mechanistic explanation of the efficacy

“…The original concept of incorporating acids into feed was based on the notion that the acids would decontaminate the feed itself and prevent Salmonella uptake by the chickens. When Iba & Berchieri (1995) inoculated feed with high doses of a S. Typhimurium strain, a commercial mixture of formic and propionic acid decreased the viability more than 1000-fold over 7 days. When broiler chicks were given the acid-treated feed that had been mixed with either S. Enteritidis, S. Typhimurium or Agona, the caecal Salmonella numbers were 7 log 10 lower than control animals at day 5 (10 2 versus 10 9 colony-forming units (cfu)/g) (Iba & Berchieri, 1995).…”

Use of formic acid to control vibriosis in shrimp aquaculture

“…Some organic acids are the natural metabolic products of organisms, and they have been used as food preservatives for a long time. Organic acids are also used as feed additives to control pathogens in animal husbandry (Iba & Berchieri 1995;Franco et al 2004). Several studies have proven that inclusion of organic acids in diets suppresses pathogenic bacterial growth in gastrointestinal tracts of poultry and swine (Iba & Berchieri 1995;Franco et al 2004).…”

“…Organic acids are also used as feed additives to control pathogens in animal husbandry (Iba & Berchieri 1995;Franco et al 2004). Several studies have proven that inclusion of organic acids in diets suppresses pathogenic bacterial growth in gastrointestinal tracts of poultry and swine (Iba & Berchieri 1995;Franco et al 2004). Other studies showed both short-chain and medium-chain fatty acids are effective bactericides of pathogenic Salmonella and Campylobacter species (Khan & Katamay 1968;Chaveerach et al 2002).…”

Efficacy of several vaccination programmes in commercial layer and broiler breeder hens against experimental challenge withSalmonella entericaserovar Enteritidis

“…The inocula were prepared from a strain of Salmonella Enteritidis PT4, kindly donated by Professor P.A. Barrow (University of Nottingham, Leicestershire, UK) and previously shown to be invasive in laying hens (Barrow & Lovell, 1991;Freitas Neto et al, 2008;Inoue et al, 2008). For ease of enumeration in organs and faeces, a spontaneous nalidixic acid and spectinomycin-resistant mutant of this strain (SENal Experimental design.…”

“…Therefore it is necessary to implement monitoring programmes based on bacteriological and serological testing to prevent the infection or to control dissemination of the organisms. Additional measures such as competitive exclusion, heat treatment of feed, incorporation of organic acids in feed, control of rodents, and so forth, can be taken as part of a comprehensive biosecurity programme (Iba & Berchieri Jr, 1995;Patterson & Bukholder, 2003).…”