Studies on the Viral Hemagglutination Inhibitors

Abstract

Following Francis' observation (1) of an inhibitor in normal serum for influenza virus hemagglutination, similar components inhibiting against a number of viruses were found to be widespread in tissue fluids and extracts. In 1951, Fastier (2) reported that the saline extract off normal mouse brain was capable of inhibiting hemagglutination by the GDVII strain of mouse encephalomyelitis virus. However, little is known about the nature of the inhibitor present in a normal mouse brain. This paper presents some characteristics of a hemagglutination inhibitor in a normal mouse brain for the virus.

Studies on the Virus Hemagglutination Using Formalin-Treated Erythrocytes

“…As is generally known there are inhibitors, substances which inhibit HA of the GD VII strain, in normal mouse brain (10).…”