Study of bacterial flora in chronic suppurative otitis media

Gulati, J.; Tondon, P. L.; Singh, Waryan; Bais, A. S.

doi:10.1007/bf03047815

Cited by 15 publications

(3 citation statements)

References 2 publications

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“…et al, and Nandy et al, reported higher incidence Goyal A et al, have lower incidence of CSOM in the first decade of life 9. In the present study, males were affected more than female which is in concordance with the other studies7,8,[10][11][12] but in contrast with the studies done by Prakash et al,Mansoor T et al, Prakash R et et al, and Loy AHC et al, …”

supporting

confidence: 93%

“…COPS showed 100% sensitivity to Vancomycin, Linezolid, and Doxcycline in our study, which is a heartening situation but calls for their judicious use so that resistance to them can be prevented and regular monitoring for emergent resistance. In case of Escherichia coli, Proteus species, and Citrobacter species, Amikacin was found to be the most effective drug to which the sensitivity was 100% while Arya C et al, 22 reported 100% sensitivity to Ceftazidime and Yang et al, 11 Sharma et al, 8 and Rao and Reddy 16 to Ciprofloxacin. When the results of various studies were compared, it became obvious that the bacteriology and antibiotic sensitivity pattern of CSOM has been changing from region to region and over time period too.…”

Section: Discussionmentioning

confidence: 99%

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Microbial profile with their antimicrobial susceptibility pattern in ear discharge of Chronic suppurative otitis media patients at a tertiary care hospital in Durgapur

Priscilla

Tiwari

Thakur³

et al. 2022

Asian J Med Sci

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Background: Chronic suppurative otitis media (CSOM) is a persistent middle ear disease with high risk of irreversible complications in absence of timely management. It is a massive health problem in India having the highest prevalence rate (>4%) requiring urgent attention. Aims and Objectives: The aim of the study was to find out risk factors, microbiological profile, with their susceptibility pattern, and of ear discharge in CSOM patients to provide guidelines for the empirical treatment. Materials and Methods: Ear discharge samples from 135 clinically diagnosed CSOM patients were collected and processed. Microbial isolates were identified and drug susceptibility testing was conducted using Kirby-Bauer disc diffusion method. Results: Pseudomonas species (59/135, 43.70%) was the predominant isolate followed by Staphylococcus species (37/135, 27.40%) while Aspergillus species (10/12, 83.33%) was the predominant fungus isolated. No anaerobic bacteria were isolated on culture. Gram-negative bacilli were most susceptible to Meropenem (100%) and Amikacin (100%) while Pseudomonas species was to Imipenem (98.35%). Gram-positive cocci showed 100% susceptibility to Vancomycin, Linezolid, and Doxycycline. Conclusion: A continuous and periodic evaluation of microbiological pattern of CSOM and antimicrobial sensitivity of isolates is necessary for forming the basis of empirical treatment which shall aid in decreasing the potential risk of complications. Further, accurate and timely identification, knowledge of the pathogens, and judicious use of antibiotics are the need of the hour.

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supporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Microbial profile with their antimicrobial susceptibility pattern in ear discharge of Chronic suppurative otitis media patients at a tertiary care hospital in Durgapur

Priscilla

Tiwari

Thakur³

et al. 2022

Asian J Med Sci

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“…Ciprofloxacin sensitivity was observed in 71% of patients, and amoxicillin-clavulanic acid sensitivity was found in 54% of patients. Several studies [11][12][13] all observed a similar sensitivity pattern. Ciprofloxacin has been determined to be the most successful medication.…”

Section: Discussionmentioning

confidence: 63%

Current Microbiological Profile and Antibiotic Sensitivity Pattern in Chronic Suppurative Otitis Media in the Post- Antibiotic Era

Agwa,

Mohamed,

Abd El Galil

et al. 2024

International Journal of Medical Arts

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Article informationBackground: Whatever the cause or pathophysiology, middle ear inflammation is known as chronic suppurative otitis media [CSOM].Because CSOM is resistant to local medicines, culture tests are regarded as the gold standard for identifying the causative agents. The aim of the work:This study aims to detect microbiological profile [Bacteria and fungi] and antibiotic sensitivity pattern [For bacterial isolates] in CSOM. Patients and Methods:This was a prospective study conducted on 100 patients with chronic suppurative otitis media who attended in the outpatient department at Al-Azhar university Hospitals from May 2022 to Feb 2023. Microbiological cultures and antibiotic susceptibility testing were performed on ear discharge samples collected from the study participants. Results:The most predominant organism causing CSOM among aerobic bacteria was S. aureus, followed by Pseudomonas Aeruginosa, E. coli and Klebsiella Pneumoniae respectively. The fungal isolate was Candida species. Ciprofloxacin and Colistin were the best medications for treating Pseudomonas aeruginosa. Ciprofloxacin and Vancomycin were effective antibiotics for S. aureus. Amikacin and colistin were the most effective antibiotics for Klebsiella Pneumoniae. Colistin and Imipenem were the most effective antibiotics for E. coli. Conclusion:Understanding the microorganisms and drug sensitivity pattern that cause CSOM and selecting appropriate antibiotics based on susceptibility testing can direct the course of therapy and minimize intracranial and extracranial problems associated with the illness.

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