Study of Canine Colon Neoplasms Using Tissue Luminescence Analysis in a High-Frequency Electromagnetic Field

Abstract

Malignant tumors of the colon present a severe medical problem, and only their timely diagnosis can provide adequate therapy. In this work, we developed and tested a screen-ing method of endoscopic analysis of canine colon neoplasms by its luminescent glow stimulated by a high-frequency electromagnetic field. Observations were made on nine dogs with endoscopically detected tumors in the large intestine. Comparative analysis showed that benign tumor and healthy tissue areas glow at the edges in a high-frequency electromagnetic field, while malignant tumors glow over their entire site. The lumines-cence histogram of healthy tissues had a one-humped appearance, while malignant tu-mors demonstrated a double-humped character, and the brightness was higher in magni-tude. Histological analysis data confirmed the luminescence results. Research on dogs can be the basis for developing an endoscopic screening method of malignant tumors of the large intestine in humans.