Objective: to increase the effectiveness of treatment of oncological diseases of the gastrointestinal tract by increasing the informative value of establishing the necessary volume of the surgical operation. Material and methods. In the high-frequency electric field visualization of the glow of 82 biopsy specimens of the large intestine taken for histological analysis was performed to solve the question of the scope of the operative intervention. Results. There was an edge luminescence in all biopsy materials in the high-frequency, while there was internal luminescence in the biopsy of a cancerous tumor. The glow covered the entire cancerous growth. By biopsy glow in the high-frequency electric field, in comparison with the endoscopy data, there were discrepancies in the diagnosis, in particular, internal glow observed in 2 patients with the initial diagnosis of "diverticulum", in 2 patients with the diagnosis of "villous tumor", 6 patients with a diagnosis of "polyp", which indicated the presence of a malignant tumor. Histological analysis confirmed this and the primary volume of the surgical operation was changed for these patients. The conclusion. The given data of visualization of luminescence of biopsy specimens can be the basis for creating an endoscopic express diagnostic method and increasing the informative value of establishing the necessary volume of a surgical operation.

Malignant tumors of the colon present a severe medical problem, and only their timely diagnosis can provide adequate therapy. In this work, we developed and tested a screen-ing method of endoscopic analysis of canine colon neoplasms by its luminescent glow stimulated by a high-frequency electromagnetic field. Observations were made on nine dogs with endoscopically detected tumors in the large intestine. Comparative analysis showed that benign tumor and healthy tissue areas glow at the edges in a high-frequency electromagnetic field, while malignant tumors glow over their entire site. The lumines-cence histogram of healthy tissues had a one-humped appearance, while malignant tu-mors demonstrated a double-humped character, and the brightness was higher in magni-tude. Histological analysis data confirmed the luminescence results. Research on dogs can be the basis for developing an endoscopic screening method of malignant tumors of the large intestine in humans.