Study of clinical presentation and histopathological patterns of ovarian cancer in a tertiary care centre

Abstract

Background:One of the leading gynecological malignancies is ovarian cancer. The current study was done to study the histopathological pattern and clinical presentation of ovarian cancer in a tertiary care centre. The objective of the study was to study the clinical presentation, histopathological types of ovarian cancer and the outcome of the management. Methods: A retrospective study of the patients treated at the M. S. Ramaiah Medical College and Teaching hospital, Bangalore from a total period of 5 years, from January 2009 -January 2014. The epidemiological data and histopathological analysis of the ovarian cancer was done. Results: In the present study, a total of 106 ovarian cancer cases were included. Majority of the patients were in the age group 40-49 years (32%). Histopathological examination of the specimens revealed that serous adenocarcinoma was the commonest (42.4%) and the least common being yolk sac tumour (0.9%). Majority (n=49, 46.2%) of the patients presented in stage III. The chief complaint was abdominal pain (n=74,69.8%) followed by abdominal distension (n=55,51.8%). Conclusions: Majority of the patients who presented to us were in the perimenopausal age group at least 2 decades earlier to the western population and many of the patients presented with abdominal pain rather than abdominal distension. These observations warrant us to screen women at an earlier age and also think of this lethal malignancy in women who present with pain and other vague symptoms.