Study of Common Infections among Children with Sickle Cell Anaemia In Saudi Arabia

Elobied, Sidieg Sheikheldin; Ramadan, Ismail N; Abdelmotaleb, Ghada S.; Younis, Abd Elmoniem A.

doi:10.21608/bmfj.2020.120869

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…25 Literature has demonstrated the association between SCD and parental consanguinity and concluded that a significantly higher incidence of inherited blood disorders was found among populations with high consanguinity marriage rates. 26 In 2003, the government of Saudi Arabia implemented a premarital screening program to reduce the incidence of SCD. 7 Therefore, these governmental efforts included premarital genetic counseling that was cost-effective in improving the awareness of parents and increasing the quality of life of children.…”

Section: Discussionmentioning

confidence: 99%

Association Between Dental Infection and Increased Incidence of Complications in Sickle Cell Disease Children: A Cross-sectional Study in Jeddah City

Felemban

Alhalees

Alattas

et al. 2023

Journal of Advanced Oral Research

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Aim: Children with sickle cell disease (SCD) are prone to many complications. However, little is known about oral infectious. This study aimed to assess the oral health status of pediatric patients with SCD and explore the associations between oral health conditions and clinical complications of SCD. Materials and Methods: A cross-sectional study was conducted in children with SCD admitted to the pediatric wards of two government hospitals in Jeddah city. The children were examined for dental caries, gingival diseases, oral lesions, and dental infections. Oral findings were compared between children who were hospitalized for vaso-occlusive crisis (VOC) or had a history of VOC in the last 6 or 12 months and those who were admitted for other reasons such as blood transfusion or other complications or had no history of VOC in the last 6 or 12 months. Results: A total of 107 children with SCD were included, with a mean age of 9.82 ± 3.82 years, of which 51 (47.7%) were females. Of the total, 58 (54.2%) were admitted because of VOC. There was a significant relationship between VOC and dental attrition ( P = 0.038), osteomyelitis, and dental abscesses ( P = 0.004). A significant association was found between the presence of dental abscesses and a history of osteomyelitis or avascular necrosis of long bones in the previous 12 months ( P = 0.001 and P = 0.041, respectively). Conclusion: Dental abscesses and non-carious lesions are likely to be associated with VOC; however, further prospective cohort studies are warranted to confirm this association and establish a causal relationship.

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Section: Discussionmentioning

confidence: 99%

Association Between Dental Infection and Increased Incidence of Complications in Sickle Cell Disease Children: A Cross-sectional Study in Jeddah City

Felemban

Alhalees

Alattas

et al. 2023

Journal of Advanced Oral Research

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Sickle Cell Disease in Children in Saudi Arabia: A Systematic Review

Hamid¹,

Albalawi²,

Alanazi³

et al. 2021

Int j pharm phytopharm res

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Background: Sickle cell disorder is commonly found in Saudi Arabia. There is no reliable information on the influence of sickle cell and the mortality rate of people aged five years and younger. Several types of research have deliberated the occurrence of SCD. The researches in the Middle East Arab Nations have established the presence of precise risk influences assembly SCD extra prevailing in this portion of the world. Aim: To review results of previous studies regarding prevalence and complications of sickle cell disease among children in Saudi Arabia Methodology: This is a systematic review, including PubMed, Google Scholar, and EBSCO that by examining randomized controlled trials, observational, and experimental studies investigates sickle cell disease among children in Saudi Arabia. Results and Conclusion:The research included 8 studies and concluded that results show elevation of the frequency of sickle cell disease in Saudi Arabia especially in the eastern and southern districts of the kingdom. Proper vaccinations and blood transfusions aimed at children at risk of complications are advised. Neonatal screening programs for sickle cell disease should be considered. Selective screening of the children at risk or with a history of consanguinity between parents rather than universal screening is more appropriate.

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Study of Common Infections among Children with Sickle Cell Anaemia In Saudi Arabia

Cited by 2 publications

References 3 publications

Association Between Dental Infection and Increased Incidence of Complications in Sickle Cell Disease Children: A Cross-sectional Study in Jeddah City

Association Between Dental Infection and Increased Incidence of Complications in Sickle Cell Disease Children: A Cross-sectional Study in Jeddah City

Sickle Cell Disease in Children in Saudi Arabia: A Systematic Review

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