Study of endometrial pathology in abnormal uterine bleeding

Parmar, Jignasha; Desai, Deepak A.

doi:10.5455/2320-1770.ijrcog20130614

Cited by 12 publications

(12 citation statements)

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“…Many of the women in this group were managed by reassurance and pharmacological treatment. Endometrial hyperplasia (25%) is the leading pathological finding in this study and is of cystic type, this figure was similar to the study done by Damle et al 4 , Arti Anvikar et al 8 and A Khare 11 . A higher incidence of 41.9% was reported by Smita et al 6 .…”

Section: Discussionsupporting

confidence: 91%

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Endometrial Aspiration Using MVA Syringe in Dysfunctional Uterine Bleeding

Singh¹,

Murmu²

2016

IJMRP

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Background: Dysfunctional uterine bleeding is a diagnosis of exclusion. Histopathological examination of endometrial aspiration is an important diagnostic tool in evaluating of DUB and a specific diagnosis could help the one to plan medical treatment and avoid unnecessary surgical intervention. This study was aimed to evaluate the endometrial Pattern in women of reproductive age presenting with DUB. Methods: Endometrial aspiration was done in the outpatient department without anaesthesia, on 110 women presenting with symptoms of dysfunctional uterine bleeding. Results: Histopathological examination of endometrial tissue showed a wide variety of endometrium ranging from normal endometrium to malignancy. Proliferative endometrium (42.72%) is the most common endometrial pattern seen in the reproductive age group followed by secretory endometrium (29.10%). The leading pathological finding in this study was endometrial hyperplasia in 26%. Endometrial carcinoma was present in 1.8% whereas tubercular endometritis was detected in 0.91% only. Conclusion: 71.82 % of women were found to have physiological endometrium. Thus, specific hormonal therapy was given to them. Endometrial aspiration by MVA syringe is a safe and effective office procedure and can be done in low resources setting.

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Section: Discussionsupporting

confidence: 91%

“…[4][5][6][7][8] DUB has great variation in the endometrial patterns and its management entirely depends upon the type of endometrial pattern. Our study like several others showed that proliferative, 11 and A Khare et al 12 . Many of the women in this group were managed by reassurance and pharmacological treatment.…”

Section: Discussionsupporting

confidence: 87%

Endometrial Aspiration Using MVA Syringe in Dysfunctional Uterine Bleeding

Singh¹,

Murmu²

2016

IJMRP

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“…In the observations of Jignashaparmar et al it was 33.3% and in the study of Doraiswamy S et al it was found in 20.5% cases. 9 In the study of Dadhania B et al 2.6% of cases were found to be having disordered proliferative endometrium.…”

Section: Discussionmentioning

confidence: 99%

Histopathology of endometrium in abnormal uterine bleeding, in correlation with thyroid profile and ultrasonography findings

Gorla¹,

Sanapala²,

Devi³

et al. 2016

Int J Res Med Sci

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INTRODUCTIONHippocrates hypothesized that the menstrual function is to purge women of their bad humors, which means that menstruation is a process by which a women's body cleans itself of unhealthy elements on a cyclical basis.¹ Many women suffer from various gynecological problems. Abnormal uterine bleeding (AUB) is the commonest presenting symptom, which has a significant morbidity and interferes with the personal, family, social and sexual life. Women of the present generation experience more number of menstrual cycles, which could be due to decreased parity and reduced length of lactational amenorrhea. 2Endometrial sampling is the gold standard for the evaluation of endometrial neoplasias, hyperplasias, metaplasias, pill induced and functional endometrial abnormalities.3 Transvaginalsonography is useful for the measurement of endometrial thickness and pattern, hyperplasias, organic causes like leiomyomas and endometrial malignancies. 4 Though newer surgical ABSTRACT Background: Abnormal uterine bleeding is the cause for many disturbances in women who are in the reproductive age group. Frequent and prolonged periods will lead to morbidity, social embarrassment, diminished quality of life and compromise of the sexual life. Methods: It is a hospital based cross sectional study conducted in the department of pathology, Andhra medical college. A total of 270 patients in the age group of 18 to 45 years were included in this study. Endometrial samples were obtained and histopathological examinations were conducted. All the clinical details and investigation reports were collected. Results: The age group of patients in this study ranged from 18 to 45 years. Maximum numbers of cases (169) were in the age group of 36 to 45 years (62.6%). Most of the patients were multipara (244 cases, 90.37%) and most common presenting complaint was heavy menstrual bleeding (198 cases, 73.3%). Majority of the patients were euthyroid (247 cases, 91.5%). Normal cyclical endometrium was found to be the commonest histopathological pattern with proliferative endometrium in 45.56% and secretory endometrium in 32.59% cases. Leiomyomas were found to be the commonest cause of abnormal uterine bleeding (15.56%). Bulky / enlarged uterus (77%) and type-IV (hyperechoic) endometrium, depicting the secretory endometrial pattern (36.66%) was the most common finding on transvaginal sonography (TVS). Conclusions: Histopathological examination is the gold standard for studying the pattern of endometrium in various causes of abnormal uterine bleeding.

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“…Complications of pregnancy were seen in 10.4% cases in which retained products of conception was the predominant cause followed by ectopic gestation, partial and complete mole [11]. Parmar et al observed that the predominant pattern was of normal cyclical endometrium (32.35%), followed by disordered (cystic, glandular or cystic-glandular) proliferative endometrium(33.33%).Benign endometrial polyp was observed in 10.78% cases, pregnancy associated conditions in 0.08% cases and endometrial hyperplasia without atypia in 0.05% cases [12]. Shajitha et al found that most common type of endometrial pattern was proliferative endometrium.…”

Section: Discussionmentioning

confidence: 99%

“…Maximum number of cases were seen in the age group of 41 to 50 years[11]. Parmar et al found that the age of patients with abnormal uterine bleeding ranged from 20-70 years and the most common age group was 40-50 years[12]. Shajitha et al included 50 cases in the age group of 40-51 years.…”

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confidence: 99%

Study of endometrial lesions in patients presenting with abnormal uterine bleeding to a Medical College Hospital

Bhowmik

Singh

Lal

2019

Trop J Pathol Microbiol

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Introduction:Abnormal uterine bleeding is common presentation in gynaecological OPD. Endometrial biopsy is helpful in proper diagnosis and ruling out malignancy. Methods: The present study was cross-sectional in nature conducted upon 164 endometrial specimens of patients suffering from abnormal uterine bleeding to assess the histopathological profile. Profile of patients, symptoms and histopathological findings were noted. Results: 41-50 years was the most common age group (32.9 %). Most common bleeding pattern observed was menorrhagia (26.8%) followed by metrorrhagia (25%). The most common histopathological finding was proliferative phase (25.6%) followed by secretory phase (22.6%). Polyp was present in 7.3% cases and endometrial carcinoma was observed in 2.4% cases. Conclusion: Histopathological assessment of endometrial specimen is helpful in diagnosis in these cases.

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Study of endometrial pathology in abnormal uterine bleeding

Cited by 12 publications

References 4 publications

Endometrial Aspiration Using MVA Syringe in Dysfunctional Uterine Bleeding

Endometrial Aspiration Using MVA Syringe in Dysfunctional Uterine Bleeding

Histopathology of endometrium in abnormal uterine bleeding, in correlation with thyroid profile and ultrasonography findings

Study of endometrial lesions in patients presenting with abnormal uterine bleeding to a Medical College Hospital

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