Study of Frozen Section and Lymph Node in Management of Mucinous Ovarian Tumors

Abstract

Introduction: Misdiagnosis of histologic type on frozen section could result in incomplete surgical staging of a more aggressive ovarian cancer, ultimately leading to an inability to prognosticate, inappropriate treatment, need for repeat surgery, and decreased survival. Study aimed to investigate the discordance rate of the frozen section with final pathology in the diagnosis of mucinous histology in ovarian tumors. Material and Methods: In this retrospective study cases of mucinous ovarian tumor on frozen section or final pathology were included from 2012 to 2018. Cases reporting a mucinous the ovarian tumor on frozen section or final pathology were identified. Frozen section results were compared with final diagnosis to calculate concordance rates. Results: Of the 38 cases reported to be mucinous on frozen section, 36 had mucinous histology confirmed on final pathology (94.7% concordance). Among the 36 mucinous tumors found to be concordant in mucinous histologic type on frozen section and final pathology, there was a 61.1% (22/36) concordance rate on the classification of malignancy. Lymph node dissection was performed in 12 of the 38 cases reported to be mucinous on frozen section. Conclusion: All of these distinctions provide significant evidence that mucinous ovarian tumors should be approached surgically as a distinct entity.