Study of Health in Pomerania (SHIP-Trend)

Jürgens, Clemens; Völzke, Henry; Tost, Frank

doi:10.1007/s00347-013-2924-9

Cited by 8 publications

(7 citation statements)

References 21 publications

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“…Arterial hypertension was found in 48.4% of all patients (33.3% in men and 50.9% in women), which does not differ from the general German population. According to recent population-based studies, the prevalence of elevated blood pressure, including controlled hypertension, in the German population is 47-69% in the age group of 55-64 and 26-60% in the group aged 45-54 [32,33]. In 2013, 34% of German men and 29% of German women over 18 years consumed nicotine on a regular basis [34].…”

Section: Discussionmentioning

confidence: 99%

Management of Cavernous Carotid Artery Aneurysms: A Retrospective Single-Center Experience

et al. 2022

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Objective: While cavernous carotid aneurysms can cause neurological symptoms, their often-uneventful natural course and the increasing options of intravascular aneurysm closure call for educated decision-making. However, evidence-based guidelines are missing. Here, we report 64 patients with cavernous carotid aneurysms, their respective therapeutic strategies, and follow-up. Methods: We included all patients with cavernous carotid aneurysms who presented to our clinic between 2014 and 2020 and recorded comorbidities (elevated blood pressure, diabetes mellitus, and nicotine consumption), PHASES score, aneurysm site, size and shape, therapeutic strategy, neurological deficits, and clinical follow-up. Results: The mean age of the 64 patients (86% female) was 53 years, the mean follow-up time was 3.8 years. A total of 22 patients suffered from cranial nerve deficit. Of these patients, 50% showed a relief of symptoms regardless of the therapy regime. We found no significant correlations between aneurysm size or PHASES score and the occurrence of neurological symptoms. Conclusion: If aneurysm specific symptoms persist over a longer period of time, relief is difficult to achieve despite aneurysm treatment. Patients should be advised by experts in neurovascular centers, weighing the possibility of an uneventful course against the risks of treatment. In this regard, more detailed prospective data is needed to improve individual patient counseling.

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Section: Discussionmentioning

confidence: 99%

Management of Cavernous Carotid Artery Aneurysms: A Retrospective Single-Center Experience

et al. 2022

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“…Local ethics committee approval was obtained to perform this study. From a sample of 8016 subjects, a total of 4420 subjects participated in the baseline examinations of the SHIP-Trend study [9–11], with a response rate of 55.14%. The examination of 486 participants took place in regional study centers without the opportunity for funduscopy.…”

Section: Methodsmentioning

confidence: 99%

“…The examiners followed standardized operational procedures for all examinations, and all data were documented electronically. The ophthalmological examinations and all the other assessments are described in detail elsewhere [11].…”

Section: Methodsmentioning

confidence: 99%

Age-Related Macular Degeneration and Associated Risk Factors in the Population-Based Study of Health in Pomerania (SHIP-Trend)

et al. 2019

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BackgroundAge-related macular degeneration (AMD) is the leading cause of visual impairment in developed countries, especially in the older population. The Study of Health in Pomerania (SHIP) is a population-based study designed to investigate risk factors and clinical disorders in the general population. In the present study, we analysed the AMD prevalence and risk factors in the north-eastern German population.Material/MethodsFrom 2008 to 2012, we collected data among participants ages 29–79 years. The study population consisted of 4420 individuals. Non-mydriatic retinal photographs were taken of 3934 participants. AMD stages were graded according to the Rotterdam Classification System and the International Classification System.ResultsPhotographs from 1854 participants were available for grading. The baseline examinations showed small hard drusen (<63 μm, stage 0b and 0c) were present in 10.7% of the participants (stage 0b in 7.5% and stage 0c in 3.2%). Earliest signs of AMD were detected in 28.68% (stage 0b in 7.5% and stage 1b in 21.18%). Late AMD (geographic atrophy and neovascular AMD, stages 4a and 4b) were identified in 0.43% (stage 4a in 0.16% and stage 4b 0.27%). Risk of AMD increased significantly with age and higher body mass index, waist circumference, hip circumference, and weight-waist-ratio. Smoking, sex, systolic and diastolic blood pressure, HbA1c, cholesterol, HDL-cholesterol, LDL-cholesterol, and triglyceride were not associated with AMD in this study.ConclusionsThe prevalence of AMD increases with age and obesity-associated factors. These results must be verified in the follow-up. Data concerning the incidence of AMD will be available after the 5- and 10-year follow-ups.

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“…Das komplexe Design der Study of Health in Pomerania (SHIP) wurde an anderer Stelle umfangreich erläutert [3,4]…”

Section: Probanden Und Erhebungsmethodikunclassified

Statische Gefäßanalyse der retinalen Blutgefäße in einer populationsbasierten Kohorte unter Berücksichtigung des Diabetes mellitus

Theophil

Jürgens

Großjohann

et al. 2017

Klin Monatsbl Augenheilkd

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Interdisciplinary investigations of possible connections between general diseases and ophthalmological changes are difficult to perform in the clinical environment. But they are gaining in importance as a result of the age-related increase in chronic diseases. The collection of health-related parameters in the Study of Health in Pomerania (SHIP) project allows to derive conclusions for the general population. The population-based SHIP trend study was conducted between 2008 and 2012 in Greifswald. The baseline cohort included 4420 subjects (response 50.1%) at the age of 20 to 84 years. The pre-existence of arterial hypertension, diabetes mellitus and smoking status were questioned in a standardized questionnaire, the blood pressure and the HbA were determined by the laboratory. The vascular diameter of retinal arterioles and venules were determined by means of non-mydriatic fundus images and the retinal arterial (CRAE) and venous equivalent (CRVE) were calculated therefrom. The association of diabetes mellitus, HbA, smoking status and blood pressure with the retinal vascular parameters was tested for age and sex with linear regression models. In 3218 subjects with evaluable standardized fundus photographs, significant associations of elevated HbA (> 6.5%), smoking status and systolic and diastolic blood pressure were found with the retinal vessel widths CRAE and CRVE. Anamnestic diabetes mellitus, on the other hand, was not associated with any of the vascular parameters. This research study reveals a relevant correlation between general diseases and the retinal blood flow in the eye. Therefore, general diseases can induce ophthalmological changes and eye examination can provide information for the assessment of general diseases.

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Study of Health in Pomerania (SHIP-Trend)

Cited by 8 publications

References 21 publications

Management of Cavernous Carotid Artery Aneurysms: A Retrospective Single-Center Experience

Management of Cavernous Carotid Artery Aneurysms: A Retrospective Single-Center Experience

Age-Related Macular Degeneration and Associated Risk Factors in the Population-Based Study of Health in Pomerania (SHIP-Trend)

Statische Gefäßanalyse der retinalen Blutgefäße in einer populationsbasierten Kohorte unter Berücksichtigung des Diabetes mellitus

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