Study of Impaired Glucose Tolerance and Hba1c in Acute Pancreatitis on the Basis of Severity

Abstract

Aim:The study was planned to evaluate the association of Impaired Glucose Tolerance and HbA1c with severity of acute pancreatitis. Material and methods: In present study Out of 133 patients diagnosed for Acute Pancreatitis; total 115 patients (n=115), of either gender of 18 to 65 years age groups were enrolled for the study. Patients with history of any acute or chronic illness like:-Diabetes Mellitus Impaired renal function, Hyperparathyroidism, Malnourished, Pregnant and lactating women and patients on calcium supplements were excluded. Result: The % of patients with impaired glucose tolerance was higher in patients suffering from severe pancreatitis. A signicant association was observed between impaired glucose tolerance and severity of pancreatitis (p ≤ 0.0001).Also signicant difference was observed in the HbA1c levels among three groups [mild, moderate and severe AP (p≤0.0001)]. Conclusion: The study concluded that a higher % of patients of severe pancreatitis group were diabetic or at risk of developing diabetes as compared to mild pancreatitis group.