Study of Interdigitated Electrode Arrays Using Experiments and Finite Element Models for the Evaluation of  Sterilization Processes

Oberländer, Jan; Jildeh, Zaid B.; Kirchner, Patrick; Wendeler, Luisa; Bromm, Alexander; Iken, Heiko; Wagner, Patrick; Keusgen, Michael; Schöning, Michael J.

doi:10.3390/s151026115

Cited by 36 publications

(26 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another concept to improve the W / L ch ratio of OECTs at limited electrode area are interdigitated electrode (IDE) arrays. IDEs facilitate a significant increase of the channel width and consequently also the W / L ch ratio in comparison to conventional architectures without increasing the device area and its overall capacitance . Hempel et al reported on the fabrication of large area (200 µm × 200 µm) OECTs with interdigitated electrode arrays and their utilization for sensing of clusters of cardiac cells.…”

Section: Introductionmentioning

confidence: 99%

Tuning Channel Architecture of Interdigitated Organic Electrochemical Transistors for Recording the Action Potentials of Electrogenic Cells

Liang

Brings

Maybeck

et al. 2019

Adv Funct Materials

View full text Add to dashboard Cite

Organic electrochemical transistors (OECTs) have emerged as versatile electrophysiological sensors due to their high transconductance, biocompatibility, and transparent channel material. High maximum transconductances are demonstrated facilitating the extracellular recording of signals from electrogenic cells. However, this requires large channel dimensions and thick polymer films. These large channel dimensions lead to low transistor densities. Here, interdigitated OECTs (iOECTs) are introduced, which feature high transconductances at small device areas. A superior device performance is achieved by systematically optimizing the electrode layout regarding channel length, number of electrode fingers and electrode width. Interestingly, the maximum transconductance (g max ) does not straightforwardly scale with the channel width-to-length ratio, which is different from planar OECTs. This deviation is caused by the dominating influence of the source-drain series resistance R sd for short channel devices. Of note, there is a critical channel length (15 µm) above which the channel resistance R ch becomes dominant and the device characteristics converge toward those of planar OECTs. Design rules for engineering the performance of iOECTs are proposed and tested by recording action potentials of cardiomyocyte-like HL-1 cells with high signal-to-noise ratios. These results demonstrate that interdigitated OECTs meet two requirements of bioelectronic applications, namely, high device performance and small channel dimensions.

show abstract

Section: Introductionmentioning

confidence: 99%

Tuning Channel Architecture of Interdigitated Organic Electrochemical Transistors for Recording the Action Potentials of Electrogenic Cells

Liang

Brings

Maybeck

et al. 2019

Adv Funct Materials

View full text Add to dashboard Cite

show abstract

“…The use of capacitive interdigitated electrodes (IDE) has been discussed already in several papers, ranging from gas sensors to liquid sensors [2][3][4][5]. In general, these electrodes are coated with responsive layers that absorb the target molecules.…”

Section: Approachmentioning

confidence: 99%

Multiparameter Sensor Array for Gas Composition Monitoring

Boersma¹,

Sweelssen²,

Blokland

2018

Eurosensors 2018

View full text Add to dashboard Cite

In the energy transition from fossil to renewable resources, gas is foreseen to play an important role. However, the composition of the gas is expected to change due to a wider variation of sources. In order to mitigate potential challenges for distributors and end-users, a new low-cost gas composition sensor was developed that will be able to monitor the composition and energy content of these gas sources, ranging from biogas to liquid natural gas (LNG). Together with industrial and academic partners a gas sensor was realized that can be inserted in an existing gas grid. A first demonstrator was realized that was small enough to be used in low and medium pressure gas pipes (100 mbarg—8 barg). Adding the pressure and temperature data to the chip readings enables to determine the concentrations of methane, ethane, propane, butane, nitrogen and carbon dioxide, including small fluctuations in water vapor pressure and subsequently calculate the Calorific Value, Wobbe Index and Methane Number.

show abstract

“…An impedimetric biosensor based on interdigitated electrode (IDE) structures has been developed by the authors in previous work . A test microorganism (spores of Bacillus atrophaeus taken from a spore suspension based on deionized (DI)‐water) has been immobilized on the IDE structure and characterized in respect to the H 2 O 2 sterilization process.…”

Section: Introductionmentioning

confidence: 99%

“…The interpretation of the impedimetric sensor data depends on the electrical properties of the B. atrophaeus spores in air or under low‐pressure conditions. Due to the lack of research on the electrical properties of the spores, analytical methods (e.g., capacitance calculation of IDE structures by applying the complete elliptical integral of the first kind that has been described for the blank structure in our previous article) cannot be applied for verification so far …”

Section: Introductionmentioning

confidence: 99%

Experimental and Numerical Analyzes of a Sensor Based on Interdigitated Electrodes for Studying Microbiological Alterations

Jildeh

Oberländer

Kirchner

et al. 2018

Physica Status Solidi (a)

Self Cite

View full text Add to dashboard Cite

In this work, a cell-based biosensor to evaluate the sterilization efficacy of hydrogen peroxide vapor sterilization processes is characterized. The transducer of the biosensor is based on interdigitated gold electrodes fabricated on an inert glass substrate. Impedance spectroscopy is applied to evaluate the sensor behavior and the alteration of test microorganisms due to the sterilization process. These alterations are related to changes in relative permittivity and electrical conductivity of the bacterial spores. Sensor measurements are conducted with and without bacterial spores (Bacillus atrophaeus), as well as after an industrial sterilization protocol. Equivalent two-dimensional numerical models based on finite element method of the periodic finger structures of the interdigitated gold electrodes are designed and validated using COMSOL 1 Multiphysics software by the application of known dielectric properties. The validated models are used to compute the electrical properties at different sensor states (blank, loaded with spores, and after sterilization). As a final result, we will derive and tabulate the frequencydependent electrical parameters of the spore layer using a novel model that combines experimental data with numerical optimization techniques.

show abstract

Study of Interdigitated Electrode Arrays Using Experiments and Finite Element Models for the Evaluation of Sterilization Processes

Cited by 36 publications

References 15 publications

Tuning Channel Architecture of Interdigitated Organic Electrochemical Transistors for Recording the Action Potentials of Electrogenic Cells

Tuning Channel Architecture of Interdigitated Organic Electrochemical Transistors for Recording the Action Potentials of Electrogenic Cells

Multiparameter Sensor Array for Gas Composition Monitoring

Experimental and Numerical Analyzes of a Sensor Based on Interdigitated Electrodes for Studying Microbiological Alterations

Contact Info

Product

Resources

About