The work is aimed at identifying the relationship between agroecological conditions and the formation of carbohydrate-acid and phenolic grape complexes. The agro-climatic parameters of 14 cv. ‘Cabernet Sauvignon’ industrial vineyards located in five wine-growing regions of Crimea have been determined using the methods of geoinformation and mathematical modeling. According to the similarity of 9 agro-climatic characteristics, the vineyards are united into 6 clusters, significantly different from each other. The dispersion of the main and secondary metabolites of grapes, as well as technological indicators based on them in the harvest from the selected clusters, has been established. According to the combined mass concentration of anthocyanins in berries, potential amount of extractable anthocyanins, anthocyanin extractability, monophenolmonooxygenase activity, glucoacidimetric index and grape ripeness index the selected vineyard clusters are discriminated with Wilks L. = 0.09 at α<0.00001. Sugar content, active acidity index, glucoacidimetric index, and grape ripeness index were found to correlate inversely with the amount of precipitation during the growing season; anthocyanin extractability correlates directly with the Huglin and Winkler indices; monophenolmonooxygenase activity with the sum of active temperatures above 10 °C, Huglin index, total precipitation per year and growing season.