Study of Metabolic Syndrome and Its Risk Components in Patients Attending Tertiary Care Center of Uttarakhand

Abstract

Metabolic syndrome is a complex of metabolic factors which includes central obesity, insulin-resistance, dyslipidemia and hypertension. Metabolic syndrome is associated with increased risk of cardiovascular disease. This study aimed to know the rate of metabolic syndrome in outpatients presenting to medicine department of our hospital and their profile. The metabolic syndrome was diagnosed using International Diabetes Federation criteria. The parameters analyzed included age, sex, blood pressure, BMI, fasting plasma glucose, HDL and triglycerides. The rate of metabolic syndrome was 21.1 % in our study. The younger population was most susceptible to metabolic derangements. Further, females were found to be affected more than males. The extremely significant parameters were deranged fasting plasma glucose, HDL, triglycerides while hypertension was found to be insignificant. Being overweight maybe a strong predictor for presence of metabolic syndrome in our region of study, and all overweight persons should be assessed and appropriately treated to prevent future cardiovascular events.

Association Between Anthropometric Risk Factors and Metabolic Syndrome Among Adults in India: A Systematic Review and Meta-Analysis of Observational Studies

“…Half of the included studies (13 of 26) were conducted in the southern states of Tamil Nadu, Kerala, Andhra Pradesh, and Telangana ( 18 , 22 – 24 , 28 , 29 , 31 , 34 , 36 – 40 ). Nineteen were community-based studies ( 16 , 17 , 19 , 21 – 26 , 28 – 34 , 36 , 38 , 41 ), 6 were facility-based ( 18 , 20 , 27 , 35 , 37 , 40 ), and 1 ( 39 ) was a workplace-based study. The sample sizes of the included studies ranged from 112 to 9,886 participants.…”

“…Under the selection bias domain, most studies (17 of 26) had high bias risk related to representativeness of the sample ( 17 , 18 , 20 – 22 , 25 , 26 , 29 , 31 – 37 , 39 , 40 ), about 15 had high bias risk related to sample size justification ( 18 , 20 , 21 , 26 , 28 , 29 , 33 – 41 ), and 16 had high bias risk related to nonresponse ( 16 – 22 , 25 , 28 , 31 , 33 , 34 , 38 – 41 ). However, none of the studies had high risk related to ascertainment of exposure.…”

17-year follow-up of association between telomere length and all-cause mortality, cardiovascular mortality in individuals with metabolic syndrome: results from the NHANES database prospective cohort study

“…MetS is a crucial risk factor for mortality [ 21 ].MetS pathophysiology includes cellular aging and oxidative stress, both of which are associated with decreased TL. [ 22 ]。Some studies reveal that MetS patients have shortened telomeres, suggesting that telomere shortening may contribute to MetS development and progression [ 7 , 9 , 15 ].…”

Matching Body Composition Confirms Decreased Phase Angle among Diabetics Compared to Controls

“…13 Another study found the rate of metabolic syndrome to be 21 % in Uttrakh and , India and the younger population was most susceptible to metabolic derangements. 14 Another study underlines that a single value of the waist-to-height ratio (WHtR) irrespective of gender can be used as a universal screening tool for the identification of individuals at high risk of development of metabolic complications 15 and subsequent Diabetes.…”