Study of Prevalence of Spontaneous Bacterial Peritonitis in Cirrhosis of Liver With Ascites

Abstract

BACKGROUNDCirrhosis of Liver is the common hepatological disorder in clinical practice. The development of Ascites is a marker of Prognosis. Spontaneous Bacterial Peritonitis is responsible for the deterioration of the condition. Without prompt diagnosis, the diagnosis and treatment of infected Ascites may be delayed, leading to death. Study was conducted in 50 patients of Govt. General Hospital, Anantapuramu, to determine the prevalence of spontaneous bacterial peritonitis in Cirrhosis of liver with Ascites patients. Of these 50 patients, 9 patients (18%) showed features of SBP, 7 patient's (77.7%) PMN count was >250/mm 3 , 2 patient's (22.3%) culture was positive for E. coli. All cases with abdominal pain, tenderness and altered sensorium were having features of SBP. Study showed SBP more common in advanced liver disease. Presence of Jaundice had no significance, but the degree of Jaundice is an indicator of SBP. Study shown Cirrhotic patients with constitution of symptoms should be screened for SBP and started on Antibiotic therapy so that mortality can be reduced.