Study of serum calcium levels in premenopausal women and postmenopausal women

Patwa, Chetana K; Jindani, Nitesh I; Afroz, Syeda

doi:10.26611/103421

Cited by 3 publications

(4 citation statements)

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“…Calcium is a major mineral required for bone formation. It is known that calcium level decrease during menopause (10,11,24), and supplementation reduces bone loss and decreases fractures rate in individuals with low calcium level including postmenopausal women (21,23). Calcium deficiency might be the major cause of fractures in our population.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous fractures in healthy postmenopausal women aged 55+ years in two health centers: Laquintinie Hospital and General Hospital, Douala, Cameroon

Aline BAMIA,

Rama Natacha SONGUE,

Andréa ADIOGO

et al. 2024

GSC Biol. Pharm. Sci.

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Background: Women in their old age are facing some health issues due to physiological changes. It was observed many cases of osteoporosis during menopause. At that stage of their life, women undergo ovaries atrophy caused by hormonal imbalance. Estrogen deficiency is a leading cause of osteoporosis in postmenopausal women. That is why at menopause when its level drops women have fragile bones and are prone to fractures of many kinds. Fractures are associated with a high risk of morbidity which is why we aimed to identify and characterize the state of fractures in older women during menopause in our country. Method: A survey was performed at the orthopedic-traumatology and rheumatology unit of 2 different health centers: Laquintinie Hospital of Douala and Douala General Hospital (DGH). Files of postmenopausal women admitted for fracture were screened. The data were analyzed by SPSS and statistical significance was considered when P-value < 0.05. Results: 643 files of postmenopausal women admitted for fractures were analyzed. Results showed that 29% (186/643) of women at menopause aged above 55 years old had spontaneous fractures. The mean age was 71.89 years, ranging from 55 to 119 years. Falls and domestic accidents were the top two most represented causes (38.2 and 31.7 % respectively). Among those fractures, 70% happened after minimal trauma. The wrist was the favorite anatomical site for patients aged ranged between 55-64 years. As for UEF (Upper end of the femur) fracture, it increased in an age-related manner. Absence of trauma was observed the less in population aged between 55 and 64 years (11.5% ; P<0.001); and it was highest in women aged 85+ years (64%). Conclusion: Postmenopausal women in our population have disabilities due to spontaneous fractures which impact negatively their quality of life. We should spread awareness among women before they reach menopause to take suitable measures to reduce the incidence of fractures and related morbidity at a certain age.

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Section: Discussionmentioning

confidence: 99%

Spontaneous fractures in healthy postmenopausal women aged 55+ years in two health centers: Laquintinie Hospital and General Hospital, Douala, Cameroon

Aline BAMIA,

Rama Natacha SONGUE,

Andréa ADIOGO

et al. 2024

GSC Biol. Pharm. Sci.

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“…[9], [10] It also partly agrees with the work of Farasat et al which reported higher serum TSH levels and low serum T3 and T4 levels were observed in postmenopausal females. [11]Significant average higher systolic and diastolic blood pressure finding may not be directly linked to the activity of the thyroid gland. It could be due to degenerative changes associated with age like arteriosclerosis.…”

Section: Discussionmentioning

confidence: 99%

“…[10] This inhibits thyroid action and lowers the rate of metabolism in the body. Studies on the effect of menopause on thyroid function are commonly associated with reduced effective thyroid hormones, [11]- [13] and the fall in estrogen levels at menopause is linked to some disorders including cardiovascular diseases and the clinical presentation of pre-existing thyroid diseases, and other comorbidities. [14], [15] Increase in age and BMI has also been implicated in the changes in thyroid function.…”

Section: Introductionmentioning

confidence: 99%

Assessment Of The Effect Of Menopause On Thyroid Function In South East,Nigeria

A Duru,

Onyenemezu,

D Okeke

et al. 2023

IJHMR

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Menopause marks the end of a woman’s reproductive life and is associated with significant physiological changes. The thyroid gland plays an important role in regulating overall body metabolism including sexual development and reproductive function. Worldwide, thyroid gland diseases are among the most common endocrine disorders in females, especially those in menopause. This study evaluated the effect of menopause on thyroid function. Methodology: It was a case-control study among post-menopausal women in Nnewi, Anambra, Nigeria with pre-menopausal women serving as controls. Sampling was by simple random method and comprised 45 post-menopausal women matched with 45 premenopausal women in a ratio of 1:1. Data was obtained with the use of a semi-structured questionnaire. The subjects’ blood samples were taken and assayed for thyroid stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3) by ELISA technique. Their body mass index (BMI) and blood pressure were obtained using standard procedures. Result: The mean serum levels of free T4 and TSH in the menopausal individuals were significantly higher compared to the premenopausal group. Following linear regression analyses with adjustment for age and BMI, the the average level of TSH and free T4 were higher in the study group, while free T3 level was lower. Also, systolic and diastolic blood pressure was significantly higher in the study group than in the control group. Conclusion: The findings suggest that menopause is associated with reduced thyroid function and could as a result play a role in cardiovascular disease play a role in cardiovascular dysfunction among women

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“…Calcium serves as a crucial component of the body's skeleton, and its adequate supply in the diet is essential, particularly in the context of reduced endogenous synthesis. This becomes especially important in cases of endocrine problems to support the maintenance of healthy bones and teeth [37,38]. The body's regulation of calcium metabolism is orchestrated by vitamin D, which exerts its influence on the gastrointestinal tract, kidneys, and skeleton.…”

Section: Hormones and Vitaminsmentioning

confidence: 99%

Etiopathogenesis of Dental Caries

Barani-Sveçla,

Buleshkaj

2024

Dentistry

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Dental caries, as a pervasive and complex global health issue affecting individuals of all ages, is influenced by a multitude of factors. These factors encompass the interplay of demineralization and remineralization processes, dietary and oral hygiene practices, salivary composition and flow, tooth morphology, genetics, fluoride exposure, and environmental and socioeconomic variables. This chapter analyzes three categories of factors that cause dental caries, such as: general, local, and iatrogenic factors. Initially, the genetic predisposition, gender-related hormonal fluctuations, aging, immunological elements, pregnancy-related changes, chronic diseases, hormonal disorders, vitamin levels, and socioeconomic factors are included in general factors that contribute to the susceptibility to dental caries. Moreover, to understand and mitigate caries risk, it is pivotal to analyze local factors such as dental morphology, oral hygiene, and the vital role of saliva. Additionally, premature loss of primary teeth, crowding, orthodontic treatment, dental fillings, and prosthetic dental work can lead to iatrogenic issues affecting oral health. Recognizing the multifaceted nature of dental caries, susceptibility underscores the necessity for comprehensive strategies in oral health care. Therefore, this chapter underlines that proper oral care, preventive measures, and meticulous attention during dental procedures are paramount for maintaining optimal oral health.

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Study of serum calcium levels in premenopausal women and postmenopausal women

Cited by 3 publications

References 0 publications

Spontaneous fractures in healthy postmenopausal women aged 55+ years in two health centers: Laquintinie Hospital and General Hospital, Douala, Cameroon

Spontaneous fractures in healthy postmenopausal women aged 55+ years in two health centers: Laquintinie Hospital and General Hospital, Douala, Cameroon

Assessment Of The Effect Of Menopause On Thyroid Function In South East,Nigeria

Etiopathogenesis of Dental Caries

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