Study of serum uric acid levels in essential hypertension

Abstract

Background: Hypertension is a major public health problem in developed and developing countries. Objective: to determine the prevalence and association of hyperuricemia with diagnosed cases of essential hypertension. Material and Methods: A hospital based cross sectional study was conducted at Department of General Medicine in a Medical College. Results: Out of the total 235 cases with hypertension, 83.8% were in stage I hypertension while 16.2% were in stage II hypertension. Prevalence of hyperuricemia was seen as 27.7% among cases with hypertension. Prevalence of hyperuricemia was 23.4% in cases with stage I hypertension while it was 50% in cases with stage II hypertension (p<0.01). Mean Systolic (153.2 vs 149.8 mmHg) and diastolic (99.8 vs 96.9 mm Hg) blood pressure was significantly more in cases with hyperuricemia (p<0.01). A significant correlation was observed between serum uric acid levels and systolic and diastolic blood pressure i.e. serum uric acid levels increases with increase in blood pressure (p<0.01). Conclusion: Prevalence of hyperuricemia was significantly higher in diagnosed subjects with essential hypertension, affecting every one out of four individual. Mean serum uric acid levels were significantly associated with increase in systolic and diastolic blood pressure.

study to compare the effectiveness of inspiratory muscle training versus alternative nostril yoga breathing on blood pressure, resting heart rate and quality of life in essential hypertension

“…3,4 The common causes of secondary hypertension are endocrine and structural disorder like congenital adrenal hypertension, Cushing syndrome, deoxycorticosteriod producing tumor, renin-secreting tumor, Little's syndrome, and aldosteronism. 5 Hypertension and its complications like stroke, congestive heart failure, kidney failure, and heart attack are largely responsible for morbidity and mortality in all age groups. It also creates social, personal, and financial issue, the cost of which is enormous.…”

“…Drugs remain the mainstay of hypertension management. 5 However, antihypertensive drugs are not without their side effects and long-term complication. Alternative non-pharmacological management includes various approaches like a low salt diet, meditation, relaxation, biofeedback, and therapeutic exercise to control blood pressure.…”