Study of the antioxidant properties of phosphorylated phenols

Antonova, N. A.; Kolyada, M. N.; Осипова, В. П.; Pimenov, Yu. T.; Берберова, Н. Т.; Tyurin, V. Yu.; Gracheva, Yu. A.; Милаева, Е. Р.

doi:10.1134/s0012500808030051

Cited by 17 publications

(10 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Obviously, the pro‐oxidant effect of triphenylantimony(V) dibromide is associated with direct interaction with SH groups of proteins or with hydrolysis product Ph 3 SbBr 2 –[Ph 3 SbBr] 2 O . It is worth noting that a promoting effect of Ph 3 SbBr 2 on LP is less pronounced in comparison with tin(IV) organometallics . A decrease in TBARS level in the liver homogenate model system with time (Table ) is probably connected with reduction of Ph 3 SbBr 2 to Ph 3 Sb.…”

Section: Discussionmentioning

confidence: 97%

The influence of some triphenylantimony(V) catecholates and o‐amidophenolates on lipid peroxidationin vitro

Smolyaninov

Antonova

Poddel’sky

et al. 2012

Applied Organom Chemis

View full text Add to dashboard Cite

A number of catecholates (complexes 1-3, 6) and o-amidophenolates (complexes 4, 5) of triphenylantimony(V) was examined in the process of lipid peroxidation of liver homogenates and sperm of Russian sturgeon (Acipenser gueldenstaedti B.), and human red blood cells. It was shown that the influence of complexes 1-6 on lipid peroxidation process in model systems depends on the nature of redox-active ligand and varies from weak anti-and pro-oxidant (catecholates 1, 6) to pronounced antioxidant (catecholates and o-amidophenolates 2-5). It was found that the complexes 2-5 are the more effective inhibitors of lipid peroxidation than standard antioxidant ionol.

show abstract

Section: Discussionmentioning

confidence: 97%

The influence of some triphenylantimony(V) catecholates and o‐amidophenolates on lipid peroxidationin vitro

Smolyaninov

Antonova

Poddel’sky

et al. 2012

Applied Organom Chemis

View full text Add to dashboard Cite

show abstract

“…1). The promotion effect of OTs upon oxidation of oleic ((Z)-9-octadecenoic) acid (Petrosyan et al, 2002), sturgeon liver lipids (Antonova et al, 2008), lipids of fish feed (Osipova et al, 2017) by O 2 has been previously found. Most of the carbonyl by-products derived from lipid peroxidation were toxic, since they could easily diffuse through membranes and could covalently modify important biomolecules far from their unmodified state (Negre-Salvayre et al, 2008).…”

Section: Resultsmentioning

confidence: 81%

The Effect of Tin Compounds on the Lipid Peroxidation Level of Russian Sturgeon Fresh and Cryopreserved Sperm

Kolyada

Осипова

Берберова

et al. 2020

EREM

View full text Add to dashboard Cite

The effect of organotin compounds (OTs) on the accumulation of the lipid peroxidation (LPO) carbonyl by-products, which react with thiobarbituric acid (TBARS) in fresh and cryopreserved sperm of Russian sturgeon, was studied. It was found that incubation (1 hour) of Russian sturgeon sperm with OTs (CH3SnCl3, (CH3)2SnCl2, (CH3)3SnCl, (n-C4H9)2SnCl2, (n-C4H9)3SnCl, (C6H5)2SnCl2, (C6H5)3SnCl) in concentration 0.1 mM led to the promotion of the accumulation of TBARS in native semen. Dimethyl- (DMT) and diphenyltin dichlorides (DPT) exhibited the greatest promoting activity, and the LPO level of both native and cryopreserved sperm of Russian sturgeon, including those in modified Stein's cryomedium, increased in the presence of these compounds. It was found that Russian sturgeon's cryopreserved sperm had lower sensitivity to the promotion of sperm LPO by DMT and DPT compared with the native sperm. The protective effect of Stein’s cryomedium decreased in the presence of the studied OTs. The results suggest that accumulation of OTs by gonad of fish is another stress factor affecting the cell productivity in the cryopreservation process.

show abstract

“…The in vivo study has been performed for the most active compounds using fish (Asipenser gueldenstaedti B.) and Wistar rats [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42].…”

Section: Metal Complexes Based On 26-di-tert-butylphenolsmentioning

confidence: 99%

Metal-Based Antioxidants - Potential Therapeutic Candidates for Prevention the Oxidative Stress - Related Carcinogenesis: Mini-Review

Милаева¹

2011

CTMC

View full text Add to dashboard Cite

The oxidative stress that is associated with the abnormal level of reactive oxygen species (ROS) is considered to be involved in the carcinogenesis process. The antioxidative defense system in the living organism regulates the toxic impact of ROS and there is strong evidence that the antioxidants prevent carcinogenesis. This review will focus on a novel approach to design synthetic metal-based antioxidants and to study their in vitro, ex vivo and in vivo activities in the cellular oxidation processes that might be involved in promotion of carcinogenesis. The antioxidants are divided into several groups depending on the nature of the ligands used: 2,6-dialkylphenols, flavonoids, polyphenols, peptides, purines, pyridines and their derivatives. Some currently achieved results in testing metal complexes as antioxidants show that they could potentially facilitate the scavenging of excess ROS, and thus restore redox balance in the damaged cells and organs. Therefore there is a strong need of the design of novel potential therapeutic candidates for prevention the oxidative stress-related carcinogenesis based on metal complexes.

show abstract

Study of the antioxidant properties of phosphorylated phenols

Cited by 17 publications

References 1 publication

The influence of some triphenylantimony(V) catecholates and o‐amidophenolates on lipid peroxidationin vitro

The influence of some triphenylantimony(V) catecholates and o‐amidophenolates on lipid peroxidationin vitro

The Effect of Tin Compounds on the Lipid Peroxidation Level of Russian Sturgeon Fresh and Cryopreserved Sperm

Metal-Based Antioxidants - Potential Therapeutic Candidates for Prevention the Oxidative Stress - Related Carcinogenesis: Mini-Review

Contact Info

Product

Resources

About