With the fast progress of infrastructure projects, super-large cross-section projects are constantly emerging, and, therefore, engineering challenges and problems are increasing. Taking the triple-arch tunnel project in the turn-back line section of Santunbei Station in Urumqi Metro Line 1# as a case study, this research applied numerical simulation software Midas GTS/NX 2022 for the analysis of tunnel force and deformation in triple-arch cross-sections under different support forms of partition wall. Following the optimization of the support design of the mixed partition wall to a single straight wall, the following analytical results were obtained: surface settlement was decreased by 21.15% at the original cross-section; maximum values of principal stress and displacement of partition wall were decreased by 6.73 and 10.64%, respectively; and corresponding values for initial support structure were decreased by 21.47% and 54.74%, respectively. Meanwhile, combined with comparative analysis of engineering measurement and numerical simulation results, surface settlement and vault deformation were found to be similar to the optimized simulation results, which not only verified the reliability of simulation results but also ensured the safe and smooth construction of the project, greatly improving construction efficiency and saving construction time and cost.