Study of Umbilical Cord Blood Lipid Profile in Term and Preterm Babies

Nazeer, Sirajuddin; Nirmaladevi, K.; Mythili, B; Saravanan, B.; Thangavel, A.

doi:10.14260/jemds/2015/1875

jemds

2015

DOI: 10.14260/jemds/2015/1875

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Study of Umbilical Cord Blood Lipid Profile in Term and Preterm Babies

Sirajuddin Nazeer¹,

K. Nirmaladevi²,

B Mythili³

et al.

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Cited by 2 publications

References 8 publications

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Profile of cord blood lipids in term newborns in parakou (Benin)

Gomina¹,

Obossou²,

Amevor³

et al. 2020

IJCBR

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Lipid profile abnormalities at birth indicate that initial genetic inheritance is already at risk of developing a cardiovascular disease. Investigate the profile of umbilical cord blood lipids of term newborns in Parakou (Benin). This research work was a cross-sectional study with descriptive and analytical purpose, based on prospective collection of data. It involved term newborns recruited through complete census in three health-care facilities located in the city of Parakou (Republic of Benin), after the informed consent read and approved by their respective mothers and ethics advice. The study data were collected from March 1 to May 30, 2017 by measurements of anthropometric and lipid parameters from umbilical cord blood using endpoint enzymatic methods. LDL cholesterol was obtained by Friedewald formula. A total of 120 newborns were recruited (60 males and 60 females). Their mean weight was estimated at 2992.68 ± 355.08 g with extremes from 2120 to 3125 g. The mean values of lipid parameters were: total cholesterol (0.68 ± 0.25 g/L), HDL cholesterol (0.29 ± 0.12 g/L), LDL cholesterol (0.31 ± 0.16 g/L) and triglyceride (0.39 ± 0.27 g/L). There was no significant difference in mean values of newborns ’ lipid parameters between both sexes (p > 0.05). Total cholesterol and HDL cholesterol were normal, respectively in 75.83% and 85% of cases; hypotriglyceridemia was observed in 61.67% of newborns.

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Profile of cord blood lipids in term newborns in parakou (Benin)

Gomina¹,

Obossou²,

Amevor³

et al. 2020

IJCBR

View full text Add to dashboard Cite

show abstract

Comparative study of cord blood lipid profile in relation to gestational age, birth weight, and sex

Kaur¹,

Masand²,

Tomar³

2019

Indian J Child Health

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Objectives: The objective of the study was to compare the cord blood lipid levels in healthy newborns according to gestational age (GA), weight, and sex. Methods: This study included 1000 healthy term and preterm neonates after obtaining parental consent at birth. The GA was confirmed using New Ballard Score. Fenton’s growth charts were utilized to classify study subjects as appropriate for GA, small for GA, and large for GA at birth. Lipid profile was measured by enzymatic colorimetric method. Serum low-density lipoprotein-cholesterol (LDL-C) was calculated by Friedewald’s formula. Results: Preterm neonates with GA of 28–36 weeks had higher mean total cholesterol, LDL, very LDL, and triglycerides levels than term neonates in contrast to their mean high-density lipoprotein (HDL) levels which was significantly lower as compared to that of term neonates. A statistically significant decline in all lipid fractions was observed with an increase in birth weight from <1.5 kg to ?2.5 kg. Females had higher lipid fractions in comparison to male neonates; however, only the difference in HDL levels was statistically significant (p<0.001). Conclusion: Low birth weight neonates exhibit higher lipid levels at birth giving scope for future research and regular follow-up of these high-risk neonates.

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Study of Umbilical Cord Blood Lipid Profile in Term and Preterm Babies

Cited by 2 publications

References 8 publications

Profile of cord blood lipids in term newborns in parakou (Benin)

Profile of cord blood lipids in term newborns in parakou (Benin)

Comparative study of cord blood lipid profile in relation to gestational age, birth weight, and sex

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