Using biomass as a renewable energy source has earned tremendous interest from researchers in recent decades, especially because the technology is environmentally benign. This article reviews the recent methods for generating biogas from water hyacinth (WH, Eichornia crassipes), arguably the world’s most evasive aquatic macrophyte. Therefore, various economic, environmentally benign, and renewable procedures that enhance biogas production from WH biomass are reviewed. WH has been co-digested with numerous waste types, including poultry droppings, municipal wastes, animal tissue wastes, pig wastes, cow dungs, etc., recording varying success degrees. Other studies focused on optimizing the operation parameters, such as mixing ratio, contact time, pH, temperature, organic loading rate, etc. We observed that most attempts to generate biogas from WH alone were not promising. However, when co-digested with other biomasses or wastes, WH either increases the process rate or improves the methane yield content. Also, the potential of WH as a phytoremdiator-cum-biogas source was investigated. This chapter provides mathematical models, scale-up installation models, and specific experimental results from various studies to guide future study plans toward optimizing CH4 generation from WH co-digestion.