Study on Immunostimulatory Property of Few Seaweeds Injected Intraperitoneally

Radhika, D.

doi:10.22159/ijcpr.2017v9i4.20978

Cited by 4 publications

(2 citation statements)

References 11 publications

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“…From the literature reports [19], it was confirmed that not much research work has been done regarding the bioactive compounds from Oedogonium intermedium. All the three solvent extracts viz., cold-and hot-water extracts and methanol extracts were made dry by suction and keeping in a hot air oven set at 50 ° C. They were then mixed with pre-warmed silica and introduced into three separate columns (first one packed with methanolic extract, a second column with hot aqueous and the third one with cold aqueous extract of Oedogonium intermedium), each charged with silica gel, 60-120 mesh (500 g) for chromatographic separation.…”

Section: Phytochemical Isolationmentioning

confidence: 98%

Extraction, Isolation of Active Principles, Anti-Bacterial and Wound Healing Activity of the Marine Algal Species Oedogonium Globosum and Oedogonium Intermedium

Meenakshisundaram

Govindaraj

Sivasubramaniam

et al. 2021

Int J Pharm Pharm Sci

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Objective: Algae is the undisputed treasures of the sea and are a valuable raw material, providing unlimited opportunities for new drug discoveries. Marine algal products are in demand in the international market in the form of standardized algal extracts or semi-finished products. Methods: Aqueous and methanolic extracts of Oedogonium globosum and Oedogonium intermedium species were obtained maceration and hot percolation. The active principles from O. intermedium were isolated, purified by column chromatography, and characterized by spectral studies IR, λmax, 1HNMR and MS. The extracts of Oedogonium species were screened for their anti-microbial effects, acute dermal irritation and wound-healing activity studies. Results: Comparing to Oedogonium intermedium (45 %, 90 %, 87 %), very low extractive yields were obtained for Oedogonium globosum (10.80 %, 37 %, 28 %). At phytochemical screening, Terpenoids, Flavanoids and, Glycans were found to be present in a significant amount and upon their isolation, it was found that a collection of fractions from cold extract with Rf value in the range 0.32-0.34 as Glycans and those from the hot extract with 0.40-0.72 as Flavanoids and those from methanolic extracts with 0.23, 0.44 and 0.71 as for Terpenoids. Anti-bacterial study revealed out the fact of Oedogonium species could give higher inhibition to gram-positive than for gram-negative bacteria at (10 μg/10μl/disc) concentration. No symptoms of systemic toxicity and mortality were observed. Silver sulfadiazine, more potent in wound closure, the effect of methanolic extracts of O. intermedium (87 %) was almost at par to the standard (95 %) in action and significantly greater than O. globosum (72 %, P<0.05). Conclusion: Admittedly, Oedogonium type algal species can be known as medicinal algae with a plethora of a wide range of pharmacological activities. Thus, this research work may be considered further for extensive innovative discoveries of new lead molecules and any other pharmacological activities, in the future.

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Section: Phytochemical Isolationmentioning

confidence: 98%

Extraction, Isolation of Active Principles, Anti-Bacterial and Wound Healing Activity of the Marine Algal Species Oedogonium Globosum and Oedogonium Intermedium

Meenakshisundaram

Govindaraj

Sivasubramaniam

et al. 2021

Int J Pharm Pharm Sci

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“…Different food types including herbs have been tested for better growth and immunity of ornamental fish industry (Madhusudan et al, 2011;Radhika and Mohaideen, 2017). Production of costeffective nutritionally balanced diets of fish is the main factor affecting intensive aquaculture due to its influence on growth, health and production cost (Yeşilayer et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Effect of Ulva lactuca and Sargassum cinereum Supplemented Diets on Growth Performance of Koi Carp (Cyprinus carpio Linnaeus, 1758) Fry in Laboratory Conditions

Sudharaka¹,

Munasinghe²,

Guruge³

2021

Trop. Agric. Res.

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There is a potential to formulate cost effective aquafeeds using seaweeds in the littoral zone of the coastal belt of Sri Lanka. This study was designed to evaluate the effect of seaweed supplemented diets on the growth of Koi carp. The experimental set up consisted of a control (C) and two experimental treatments (T1 and T2). The control diet (without seaweed) and the two test diets, of which 30% of the weight of control diet was replaced by Ulva lactuca and Sargassum cinereum were fed to Koi carps in C, T1 and T2 respectively. Proximate analyses were carried out for both ingredients, and the diets were prepared following standard methods. Koi carp in fry stage belonging to the same cohort (weight 2.20±0.08 g, length 3.89±0.04 cm) were assigned to C, T1 and T2 in fiber tanks filled with 150L of water (n=20 per tank) with four replicates each. The fish were fed 5% of their body weight twice a day (09.00h and 15.00h) for 14 weeks. The length and weight measurements were recorded once in two weeks. Fish performance was compared using Body Weight Gain (BWG), Daily Growth Rate (DGR), Relative Growth Rate (RGR), Feed Conversion Ratio (FCR), Feed Efficiency (FE), Fulton's Condition Factor and survival rates. At the end 14 th week of the experiment, mean values of the weight, length, BWG, DGR showed a significant difference (p<0.05) among treatments. Tukey test revealed that FCR of the T2 and T1 were significantly different (p<0.05) from the Control and FE of T2 was significantly different (p<0.05) from the C. Condition Factor and water quality parameters did not show a significant difference (p>0.05) among treatments. There was a 100% survival rate in all groups. Aquafeeds supplemented with seaweeds showed promising results in terms of increasing growth rates of young Koi carps.

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Dietary Effect of Padina boergesenii on Growth, Immune Response, and Disease Resistance Against Pseudomonas aeruginosa in Cirrhinus mrigala

Ragunath

Ramasubramanian

2022

Appl Biochem Biotechnol

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Seaweeds are potential renewable resources in the aquatic environment. The present study was made to evaluate the in uence of seaweed Padina boergesenii incorporated with basal diet in different concentrations. The Phyto-constituents of the seaweeds were characterized by Gas Chromatography Mass Spectrometry. Diets were formulated to include seaweed meal at elevated levels from 0.5%, 2.5%, 4.5% and 6.5%. The C. mrigala fed with P.boergesenii incorporated with basal diet for a period of 45 days. The Growth parameters (weight gain, Speci c growth rate) and biochemical constituents were observed signi cantly. The fraction of extracts showed effective inhibitory activity against Pseudomonas aeruginosa. Hence, this study suggests that extracts of seaweed P. boergesenii, contain potential bioactive compounds with considerable antibiotic activity.

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Study on Immunostimulatory Property of Few Seaweeds Injected Intraperitoneally

Cited by 4 publications

References 11 publications

Extraction, Isolation of Active Principles, Anti-Bacterial and Wound Healing Activity of the Marine Algal Species Oedogonium Globosum and Oedogonium Intermedium

Extraction, Isolation of Active Principles, Anti-Bacterial and Wound Healing Activity of the Marine Algal Species Oedogonium Globosum and Oedogonium Intermedium

Effect of <em>Ulva lactuca</em> and <em>Sargassum cinereum</em> Supplemented Diets on Growth Performance of Koi Carp (<em>Cyprinus carpio</em> Linnaeus, 1758) Fry in Laboratory Conditions

Dietary Effect of Padina boergesenii on Growth, Immune Response, and Disease Resistance Against Pseudomonas aeruginosa in Cirrhinus mrigala

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