2019
DOI: 10.1136/gpsych-2018-100026
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Study on risk factors of extrapyramidal symptoms induced by antipsychotics and its correlation with symptoms of schizophrenia

Abstract: BackgroundExtrapyramidal symptoms (EPS) are one of the most common and neglected side effects during the treatment of schizophrenia. The risk factors of EPS in Chinese patients with schizophrenia and its relationship with psychiatric symptoms and mood symptoms of schizophrenia remain unknown.AimsThe main objective of this study is to explore the risk factors of EPS caused by antipsychotics and the relationship between EPS and psychotic symptoms and mood symptoms of schizophrenia.MethodThis study included 679 p… Show more

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Cited by 23 publications
(27 citation statements)
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References 28 publications
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“…At present, there are articles published on the analysis of the data in this study, and a pharmacodynamic model has been established to quantify the time-efficacy relationship of antipsychotic drugs. [31][32][33] Contributors WY and SH are responsible for the project implementation and the writing of the paper. JH is responsible for the project implementation and ethical review.…”
Section: Discussionmentioning
confidence: 99%
“…At present, there are articles published on the analysis of the data in this study, and a pharmacodynamic model has been established to quantify the time-efficacy relationship of antipsychotic drugs. [31][32][33] Contributors WY and SH are responsible for the project implementation and the writing of the paper. JH is responsible for the project implementation and ethical review.…”
Section: Discussionmentioning
confidence: 99%
“…Patients taking sodium valproate were 1.88 times more likely to develop akathisia than those taking antipsychotics only; however study done by Weng J et al . did not find out any statistically significant difference in extra-pyramidal symptoms between the two groups of patients [ 39 ].…”
Section: Discussionmentioning
confidence: 99%
“…Los síntomas extrapiramidales agudos tempranos se desarrollan con mayor frecuencia al comienzo del tratamiento con antipsicóticos o cuando se aumenta la dosis, mientras que los de inicio tardío suelen ocurrir después de un tratamiento prolongado y se presentan como discinesia tardía. Los síntomas extrapiramidales agudos son una de las principales causas de mala adherencia al tratamiento antipsicótico por la reversibilidad de los síntomas, mientras que la discinesia tardía es la que más afecta la calidad de vida de pacientes y cuidadores 23,24 .…”
Section: Tratamiento De Los Síntomas Extrapiramidalesunclassified