Study on the prevalence and incidence of urolithiasis in Korea over the last 10 years: An analysis of National Health Insurance Data

Abstract

PurposeWe aimed to analyze the incidence and prevalence of urolithiasis in Korea over the last decade using the National Health Insurance (NHI) sample cohort data.Materials and MethodsFrom January 2002 to December 2013, we enrolled sample cohort data from the NHI. Patients diagnosed with international classification of diseases code N20 or N13.2 were included. The incidence and prevalence rate was counted from the same period and patients previously diagnosed with urolithiasis were excluded. We compared the incidence and prevalence of urolithiasis by region, age, and sex, and identified the changes.ResultsTotal 1,111,828 subjects were included. Of these subjects, 36,857 had urolithiasis. The male-to-female ratio was 1.57:1, and total incidence rate was 3.27 per 1,000 person-years (1,000p-yrs). The annual incidence was lowest in 2013 (3,138 patients) and highest in 2005 (3,751 patients). Incidence rate by diagnostic code was highest in ureter stone only (2.49 per 1,000p-yrs) and was lowest in kidney and ureter stone both (0.17 per 1,000p-yrs). Prevalence gradually increased from 3,172 in 2002 and 5,758 in 2013. Jeollanam-do had the highest incidence rate of 3.70 persons per 1,000p-yrs, and Jeju had the lowest rate of 2.84 persons per 1,000p-yrs. In gender analysis, Daegu had the highest incidence (4.56) in males, Jeollanam-do had the highest incidence (3.20) in females.ConclusionsAnnual incidence remained stable, whereas prevalence gradually increased. The incidence in male was 1.57 times higher than female, and the peak incidence age was 45–49 years, with the highest incidence occurring in Jeollanam-do and the lowest in Jeju.

Kidney Stone Composition in Various Country Around the World

“…In the US, the prevalence increased from 3.2% in 1976-80 to 8.8% in 2007-10 [1]. Similar trends have also been observed in Europe and the Far East [2][3][4][5]. More recently increased rates of stone prevalence were described in regions [6] where previously the rate of prevalence was lower.…”

Escherichia coli Aggravates Calcium Oxalate Stone Formation via PPK1/Flagellin‐Mediated Renal Oxidative Injury and Inflammation

“…Renal caliculus is a common and multifactorial disease affecting the population worldwide [1][2][3], which can be triggered by metabolic disorders, ethnic factors, oxidative injury, and urinary tract infections (UTIs). Approximately 80% of urinary stone contains calcium oxalate (CaOx), and the CaOx stone is the most common type, but the mechanism of its formation remains unknown [4,5].…”

Association of meteorological factors and ambient air pollution on medical care utilization for urolithiasis: a population-based time-series study

“…Various intrinsic causative factors, such as sex, race, age, mineral metabolism, diet, fluid losses, and dehydration, and even extrinsic factors, such as geographic and meteorological factors, can influence stone formation [ 3 , 4 ]. Previous studies have reported the influence of seasonal climate on stone formation [ 5 , 6 ] and the association between ambient temperature and urolithiasis [ 7 – 9 ].…”