From the turn of the 20th century, biopreparations that quicken plant growth and development have been frequently employed. The accumulated knowledge of the mechanisms governing interactions between microorganisms and plants necessitates the use of minimal resources and energy in the targeted design of phytomicrobial systems and the optimization of their adaptability in order to increase soil fertility and plant productivity, increase plant yield, and increase plant resistance to diseases and unfavorable environmental conditions and stress factors. In the article today, enough experience has been collected on the scientific management of soil microorganism processes in the optimization of agricultural production and maintaining soil fertility, and it envisages the creation and use of microbiological preparations as the main link of intensive technologies in plant science. It is known that concentration of biomass of microorganisms using flocculants in the technological processes of production of bacterial preparations, after the stage of growth in enzymes, the stage of concentration of biomass of microorganisms from culture liquid is carried out.