“…In cases of unsuccessful conservative treatment, direct surgical repair of the leak is necessary, with traditional intracranial techniques or endoscopic endonasal techniques (9,10,20,24). The surgical management of a CSF fistula depends on the etiology of the leak, the location of the fistula and the temporal relationship of the leak to the causative factors (16,31). Surgical treatment, transcranial or endonasal, was compulsory in iatrogenic CSF leaks and in nontraumatic leakage (Fig.…”