Subcutaneous Granuloma Pyogenicum

A Case of Childhood Subcutaneous Pyogenic Granuloma (Lobular Capillary Hemangioma)

“…In 1982, Cooper and Mills were the first to report the subcutaneous variant as single lesions on the extremities of 5 male patients who ranged in age from 16 to 53 years. 4 The lesions were described clinically as subcutaneous nodules or cysts that were easily dissected from the surrounding subcutaneous tissue without unusual bleeding and without recurrence. When microscopically examined, these lesions were unmistakably PG with its "distinctive and diagnostic pattern of cellular capillary lobules separated by fibrous stroma .…”

Pyogenic granuloma over the venous component of a mixed vascular malformation

“…Similarly, pyogenic granulomas have been described in respiratory, gastrointestinal, ocular, and genitourinary mucosa, sometimes associated with anemia related to chronic bleeding . Other less frequently reported locations are the subcutis and inside large veins . It usually appears in isolation, although cases of multiple pyogenic granulomas have been described, especially with recurrences after treatment, as satellite lesions .…”

Pseudosarcomatous Angioplasia: Atypical Presentation of Pyogenic Granuloma

“…Like other pyogenic granulomas, they are benign and manifest no tendency to spread within the bloodstream . Cooper and Mills suggested “lobular capillary hemangioma” as a more accurate term that could include the entire category of polypoid, intradermal, subcutaneous, and intravenous hemangiomas that have identical microscopic findings to pyogenic granuloma …”

“…These lesions may simulate angiosarcoma with metastatic lesions or melanoma . Subcutaneous pyogenic granulomas may present as nonspecific subcutaneous nodules of short duration commonly located on the upper extremities …”