Let {X k , k = 1, 2, . . .} be a sequence of independent random variables with common subexponential distribution F , and let {w k , k = 1, 2, . . .} be a sequence of positive numbers. Under some mild summability conditions, we establish simple asymptotic estimates for the extreme tail probabilities of the weighted sum n k=1 w k X k and of the maxima of weighted sums max 1≤m≤n m k=1 w k X k , subject to the requirement that they should hold uniformly for n = 1, 2, . . .. A direct application of the result is to risk analysis, where the ruin probability is to be evaluated for a company having the gross loss X k during the kth year with a discount or inflation factor w k .