Subjective and objective evaluation of alertness and sleep quality in depressed patients

Matouŝek, M; Červená, Kateřina; Závěšická, Lucie; Brunovský, Martin

doi:10.1186/1471-244x-4-14

Cited by 35 publications

(23 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…14 Despite a quick improvement of several subjective sleep parameters on PSQI during the first week and a continuing improvement during the following weeks, we only observed a significant change of some objectively assessed sleep parameters in the early phase of the study, which is similar to studies by Argyropoulos et al 16 and Matousek et al, 17 both carried out on outpatients with less depression. These findings also point to different time scales on which subjective and objective aspects of sleep improve.…”

Section: Discussionsupporting

confidence: 84%

Night Locomotor Activity and Quality of Sleep in Quetiapine-treated Patients With Depression

Todder¹,

Caliskan²,

Baune³

2006

Journal of Clinical Psychopharmacology

View full text Add to dashboard Cite

This research assesses the development of the night-activity rhythm and quality of sleep during course of treatment among patients with unipolar or bipolar depression and receiving antidepressant treatment plus quetiapine. Twenty-seven patients with major depressive episode were included into a 4-week follow-up study and compared with 27 healthy controls. Motor activity was continuously measured with an electronic wrist device (actigraphy), sleep was assessed with the Pittsburgh Sleep Quality Index, and patients were clinically assessed with the Hamilton depression score. All patients received a standard antidepressant treatment plus quetiapine. Whereas we found a rapid and maintaining improvement of subjective sleep parameters during the 4-week study, we observed a rapid improvement of some objective sleep parameters (actigraph) within the first week, but no further significant change of objective sleep parameters during the rest of the study. Another main finding of this study is that changes of subjectively and objectively assessed sleep parameters do not necessarily reflect clinical improvement of depression during the same timeline. Despite partial clinical remission, objective sleep parameters still showed significantly different patterns compared with controls. This study is the first to examine the effect of quetiapine on locomotor activity alongside with sleep in depression. As the studied patients with depression showed improvement in subjective and objective sleep parameters, quetiapine may be a promising drug for patients with depression and insomnia. Further studies need to investigate in detail the timeline of clinical remission and alterations of objective and subjective sleep parameters.

show abstract

Section: Discussionsupporting

confidence: 84%

Night Locomotor Activity and Quality of Sleep in Quetiapine-treated Patients With Depression

Todder¹,

Caliskan²,

Baune³

2006

Journal of Clinical Psychopharmacology

View full text Add to dashboard Cite

show abstract

“…As with cognitive function, studies examining perceived sleep and objective sleep measures (such as actigraphy or EEG) have shown strong positive correlations, suggesting agreement on this particular functional outcome, [85] whereas others show poor agreement. [86] The influence of disease severity on the relationship between perceived and objective functioning may also be important, and should be better investigated. Some data suggest that increased severity of depression is associated with more functional impairments, such as cognitive complaints in the elderly, [87] although the relationship between these complaints and objective performance has been less frequently studied.…”

Section: Self-reported Versus Objective Assessment Of Functional Impamentioning

confidence: 99%

Defining and Measuring Functional Recovery from Depression

2010

View full text Add to dashboard Cite

Depression is associated with significant functional impairment and reduced quality of life. Disruptions occur both globally as well as in specific functional areas such as work, interpersonal relationships and cognitive function. From both a clinical and research perspective, much focus has been given to the resolution of symptoms associated with depression, while relatively little attention has been given to functional improvements. Definitions of remission in depression are most frequently based on achieving a cut-off score on clinical rating scales of depressive symptoms. Research in this area has sparsely included psychosocial function or health-related quality of life as a primary outcome measure in clinical trials. However, the need to fully understand the impact of depression and its treatments on functioning is great, given the existing evidence of the profound effect that depression has on function. Even mild depressive symptoms and subsyndromal depression result in functional impairment and reduced quality of life, and untreated residual depressive symptomatology can result in an increased likelihood for relapse of the fully symptomatic disorder (i.e. major depressive disorder). Therefore, clinicians and researchers alike need to broaden the focus of treatment to encompass not only the specific symptoms of depression, but the functional consequences as well. Many tools have been developed to assess function and quality of life, both globally as well as within specific domains. In addition, the effect of residual symptoms associated with functional impairment (i.e. insomnia, fatigue, pain [somatic] symptoms and cognition) in depression, even independently of depressive symptoms, warrants evaluation and monitoring. Recommendations for evaluating functional outcomes include: (i) adequately assessing functional impairment; (ii) identifying and/or developing treatment plans that will target symptoms associated with functional impairments; and (iii) monitoring functional impairments and associated symptoms throughout the course of treatment. The development of treatments that specifically target improvements in functional impairments is needed, and may require the use of novel treatment strategies.

show abstract

“…7 In addition, many patients with major depressive disorder have poor insight into their sleep quality, often misestimating their sleep latency, sleep time, and sleep duration. 17 …”

Section: Sleep Disturbances In Major Depressive Disordermentioning

confidence: 99%

Sleep Disturbances in Depression

Murphy

Peterson

2015

Sleep Medicine Clinics

238

140

View full text Add to dashboard Cite

Subjective and objective evaluation of alertness and sleep quality in depressed patients

Abstract: Background: The reliability of the subjective statements reports on disturbed night sleep and alertness in the daytime was assessed by their correlation to the objective indicators in patients with mild deprsssion.

Cited by 35 publications

References 10 publications

Night Locomotor Activity and Quality of Sleep in Quetiapine-treated Patients With Depression

Night Locomotor Activity and Quality of Sleep in Quetiapine-treated Patients With Depression

Defining and Measuring Functional Recovery from Depression

Sleep Disturbances in Depression

Contact Info

Product

Resources

About