Subjective Memory Complaints and Cognitive Impairment in Older People

Reid, Louise M.; MacLullich, Alasdair M.J.

doi:10.1159/000096295

Cited by 558 publications

(553 citation statements)

References 115 publications

Supporting

Mentioning

491

Contrasting

Unclassified

Order By: Relevance

“…While a few studies have shown a general tendency towards lower cognitive performance in the presence of depressive symptoms (Gallacher et al, 1999;Moraes et al, 2010), results regarding subjective memory complaints or a positive family history of dementia are more controversial. Some studies have found worse performances on cognitive tests among subjects with memory complaints, but other investigations have made evident that memory complaints are a poor indicator of cognitive function (Reid & MacLullich, 2006). Family history of dementia is a wellknown risk factor for Alzheimer's disease; however, scarce studies have investigated the influence of this variable on the cognitive performance of healthy subjects.…”

Section: Introductionmentioning

confidence: 99%

The Relevance of Sociodemographic and Health Variables on MMSE Normative Data

Freitas

Simões

Alves

et al. 2014

Applied Neuropsychology: Adult

View full text Add to dashboard Cite

The Mini-Mental State Examination (MMSE) is the most broadly used cognitive screening instrument in clinical and research contexts. The MMSE was administered to a community-based sample of cognitively healthy adults (n=850), stratified according to several sociodemographic variables, with a distribution similar to that observed in the Portuguese population. This study aimed to analyse the influence of sociodemographic (age, gender, educational level, marital and employment status, geographic region, geographic localisation, and residence area) and health variables (subjective memory complaints of the participant and evaluated by the informant, depressive symptoms and family history of dementia) on the subjects' performance on the MMSE and to establish normative data for the Portuguese population. Educational level and age significantly contributed to the prediction of the MMSE scores, explaining 26% of its variance.Regarding health variables, only the subjective memory complaints of the participant showed a small contribution (4%) to the variance of the MMSE scores. According to these results, age and education were considered in the development of the normative data of the MMSE for the Portuguese population.

show abstract

Section: Introductionmentioning

confidence: 99%

The Relevance of Sociodemographic and Health Variables on MMSE Normative Data

Freitas

Simões

Alves

et al. 2014

Applied Neuropsychology: Adult

View full text Add to dashboard Cite

show abstract

“…3,6 It is widely recognized that depressive symptoms can mimic cognitive impairment and dementia in older patients. 7 Therefore, it has been suggested that olfactory tests could also improve differential diagnosis between dementia and depression in older subjects. [8][9][10] Clinically diagnosed depression is not consistently associated with olfactory abnormalities, and olfactory deficits observed by some authors in severely depressed subjects were relatively mild.…”

mentioning

confidence: 99%

Depressive symptoms and olfactory function in older adults

Ścińska

Wróbel

Korkosz

et al. 2008

Psychiatry Clin Neurosci

View full text Add to dashboard Cite

Aims: Neuroimaging studies suggest a significant overlap between brain regions involved in the regulation of olfaction and mood. The aim of the present study was to search for correlations between depressive symptomatology measured by the 15-item Geriatric Depression Scale (GDS) and olfactory function assessed with Sniffin' Sticks in non-demented older adults (aged 53-79 years).Methods: Taste detection thresholds were also measured by means of electrogustometry on the anterior tongue. Results:No correlation was found between the GDS scores (range: 0-12) and olfactory thresholds or olfactory identification scores. Similarly, there was no relationship between depressive symptoms and electrogustometric thresholds. Subjects (n = 25) scoring Ն5 on the GDS were classified as 'depressed' and all other individuals (n = 60) were classified as 'nondepressed'. The two groups did not differ in terms of the olfactory measures and electrogustometric threshold. Conclusion:Depressive symptoms are not associated with any major olfactory deficit in non-clinical older adults.

show abstract

“…Although older adults with affective symptoms experience SCI more commonly than those without SCI, prevalence estimates for depression and anxiety in community-dwelling elders range from 1% to 5% and 3% to 14%, respectively (Fiske, Wetherell, & Gatz, 2009;Wolitzky-Taylor, Castriotta, Lenze, Stanley, & Craske, 2010), compared with the much more common experience of SCI (Reid & Maclullich, 2006). When SCI is perceived to have a negative impact on important aspects of daily life, the influence on the development or exacerbation of depressive symptoms may be greater.…”

Section: Discussionmentioning

confidence: 99%

Subjective Cognitive Impairment and Affective Symptoms: A systematic review

2016

The Gerontologist

View full text Add to dashboard Cite

Purpose of Study: Subjective cognitive impairment (SCI) has been argued to reflect affective symptoms (i.e., depression and anxiety) rather than actual cognitive issues. Although a number of studies exist that look at the associations between SCI and affective symptoms, no review is available to aggregate this disparate literature. We addressed this gap by conducting a systematic review to better understand the relationships among SCI and affective symptoms among older adults in both community and clinical settings. Design and Methods: We reviewed available literature per the criteria of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Weight of evidence (WoE) ratings and narrative synthesis were completed for 58 articles. Results: A majority of studies focused on community-based samples (n = 40). Approximately half (53%) of the articles reviewed met high WoE criteria for the current review. Cross-sectional findings consistently identified a positive relationship among SCI and affective symptoms. Findings from available longitudinal studies (n = 9) were mixed but suggested a possible reciprocal relationship among SCI and depression. The relationship between SCI and anxiety appeared to be driven by fears over loss of function. Following consultation with health professionals, the association between SCI and anxiety was diminished or eliminated. Implications: Although SCI is consistently related to affective symptoms in older adults cross-sectionally, more longitudinal work is needed to understand their temporal relationship. Improved measurement of SCI would support a deeper understanding of the impact of SCI on psychological well-being.

show abstract

Subjective Memory Complaints and Cognitive Impairment in Older People

Cited by 558 publications

References 115 publications

The Relevance of Sociodemographic and Health Variables on MMSE Normative Data

The Relevance of Sociodemographic and Health Variables on MMSE Normative Data

Depressive symptoms and olfactory function in older adults

Subjective Cognitive Impairment and Affective Symptoms: A systematic review

Contact Info

Product

Resources

About