Submental thyroid ectopy might cause subclinical hypothyroidism in early childhood

Kočova, Mirjana; Zdraveska, Nikolina; Zdravkovska, Maja; Anastasovska, Violeta; Gjorceva, Daniela Pop

doi:10.1177/2050313x16683623

Cited by 3 publications

(4 citation statements)

References 22 publications

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“…Similar to a normal thyroid, the ectopic thyroid is susceptible to the same pathology that affects a normal thyroid, including goiters, Hashimoto's thyroiditis, benign adenomas, and malignancies. [ 7 ] The incidence of carcinoma in ectopic thyroid is reported to be about 1%. In contrast to the malignancies found in the orthotopic thyroid gland, follicular carcinoma is the most common subtype in ectopic thyroid, instead of the more common papillary subtype.…”

Section: Discussionmentioning

confidence: 99%

Submental Ectopic Thyroid in a Patient with an Orthotopic Thyroid Gland

Mak

2022

Journal of Medical Ultrasound

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Ectopic thyroid is a rare clinical disease, with the majority of the patient presented with hypo-functional thyroid tissue and absence of orthotopic thyroid gland. During embryogenesis, the thyroid gland descends from the foramen cecum to its normal position located below the larynx and hyoid bone, anterior to the 2 nd , 3 rd , and 4 th tracheal cartilaginous rings. Any defect that occurs during this period will result in ectopic thyroid. Hence, ectopic thyroid is usually found along the course of the thyroglossal duct, laterally in submandibular glands and even in distant places such as mediastinum or very rarely in sub-diaphragmatic organs. However, the presence of an orthotoptic thyroid may lead some difficulties in the diagnosis of this disease; hence, fine-needle aspiration is recommended to avoid unnecessary operation provided the patient is asymptomatic.

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Section: Discussionmentioning

confidence: 99%

Submental Ectopic Thyroid in a Patient with an Orthotopic Thyroid Gland

Mak

2022

Journal of Medical Ultrasound

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“…Thyroid ectopia accounts for nearly 60% of thyroid dysgenesis. Ectopic thyroid results from aberrant embryogenesis during its passage from the floor of the primitive foregut to the final pre tracheal location (1). Its prevalence is about 1 per 10000-30000, rising to 1 per 4000-8000 with thyroid disease (2).…”

Section: Introductionmentioning

confidence: 99%

“…Ectopic thyroid is common in females, especially in Asia. In 70-90% of cases, it is the only thyroid tissue present and can be found anywhere along its pathway of descent, and the most common location is sublingual region (1,3).…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic Dilemma due to Atypical Presentation of Sublingual Thyroid Ectopia: A Case Report

Yasmin¹,

Rahman²,

Sharmin³

et al. 2023

Bangladesh J. Nuclear Med.

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Thyroid tissue may be found in an abnormal location along the thyroglossal duct tract or other sites due to abnormal embryologic development and migration. Thyroid ectopia is an uncommon but well-documented clinical entity. In the event of any neck swelling, it should be kept as a differential diagnosis. Thyroid scintigraphy plays a very important role in diagnosing ectopic thyroid, with the complementary primary role of high-resolution neck ultrasonography (HRUS). Reported case of an 18-year-old male referred to INMAS for evaluation of a slowly enlarging submental swelling with no history of dysphagia or dyspnea was biochemically hypothyroid. Patient had a history of submental swelling that was misdiagnosed as an abscess, creating a diagnostic dilemma, as he was found to have glandular tuberculosis after surgical drainage of the lesion. Bangladesh J. Nuclear Med. 25(2): 125-127, 2022

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Ectopic submental thyroid tissue, with no evidence of orthotopic thyroid: a case report

Banezhad¹,

Askari²,

Abbasian³

et al. 2019

EJMCR

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Background: Thyroid ectopia refers to a congenital disease with abnormal descending of the thyroid gland. The most common subtype is lingual thyroid ectopia. Sublingual and submental thyroid ectopia are much less common. It may also be found in other neck locations and distant positions .70%–90% of patients with ectopic thyroid do not have eutopic thyroid tissue. It is necessary to distinguish ectopic thyroid from other causes of neck masses. Case Presentation: A 18-year-old man was referred for the evaluation of a palpable mass in the submental region. On biochemical examination, the thyroid function tests were normal while receiving levothyroxine therapy. Ultrasonography revealed a mass measuring 4.2 × 2.7 × 2.6 cm in the submental region. The thyroid scan did not show any uptake in the thyroid region. A zone of the tracer activity was noted in the central neck, compatible with the palpated mass in the submental region. CT images showed a hyperdense soft tissue in the submental region, too. Conclusion: Thyroid ectopia is a rare condition and it is often accompanied by hypothyroidism. Ectopia often occurs in lingual and sublingual locations, and submental one is less common. Thyroid scintigraphy is the best imaging modality for the detection of thyroid ectopia. For precise localization, the CT scan correlation may be needed.

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Submental thyroid ectopy might cause subclinical hypothyroidism in early childhood

Cited by 3 publications

References 22 publications

Submental Ectopic Thyroid in a Patient with an Orthotopic Thyroid Gland

Submental Ectopic Thyroid in a Patient with an Orthotopic Thyroid Gland

Diagnostic Dilemma due to Atypical Presentation of Sublingual Thyroid Ectopia: A Case Report

Ectopic submental thyroid tissue, with no evidence of orthotopic thyroid: a case report

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