2019
DOI: 10.1016/j.neuroscience.2018.11.008
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Subregion-specific Protective Effects of Fluoxetine and Clozapine on Parvalbumin Expression in Medial Prefrontal Cortex of Chronically Isolated Rats

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Cited by 31 publications
(27 citation statements)
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“…Although some studies on major depression patients have not found changes in PV expression or in PV+ cell density in the PFC (Beasley et al 2002; Rajkowska et al 2007; Sibille et al 2011), at least one found a decrease in PV gene expression (Tripp et al 2012). Similarly, anomalies in PV expressing interneurons have been also reported in animal models of major depression (Perova et al 2015; Pesarico et al 2019; Sauer et al 2015; Todorovic et al 2019).…”
Section: Introductionmentioning
confidence: 71%
“…Although some studies on major depression patients have not found changes in PV expression or in PV+ cell density in the PFC (Beasley et al 2002; Rajkowska et al 2007; Sibille et al 2011), at least one found a decrease in PV gene expression (Tripp et al 2012). Similarly, anomalies in PV expressing interneurons have been also reported in animal models of major depression (Perova et al 2015; Pesarico et al 2019; Sauer et al 2015; Todorovic et al 2019).…”
Section: Introductionmentioning
confidence: 71%
“…In rodents, CMS caused a reduction in PV neuron number in the mPFC of anhedonic rats, whereas SST density was unchanged (Czéh et al, 2018). A decrease in PV cell number was also found in rats submitted to chronic social isolation (Todorovic et al, 2019). By contrast, there was a report of increased PV expression in the PFC of female mice after 2 weeks of CUS (Shepard et al, 2016; Shepard and Coutellier, 2018).…”
Section: Gaba Interneuron-related Deficits In Depressionmentioning
confidence: 85%
“…However, others have reported decreased PV cell counts in the PFC following chronic stress (Czéh et al, 2018;Todorović et al, 2019), countering the hypothesis of increased prefrontal inhibition mediated by prefrontal PV cells. The study by Czéh et al…”
Section: Prefrontal Parvalbumin Cells and Chronic Stressmentioning
confidence: 89%