1990
DOI: 10.1016/0920-9964(90)90156-2
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Substance abuse and schizophrenia: Effects on symptoms but not on neurocognitive function

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Cited by 57 publications
(77 citation statements)
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“…Our results are in agreement with a previous study showing no differences between schizophrenia patients with (n=38) and without (n=25) a history of cannabis abuse for performance at tests assessing intelligence, memory, learning, fluency, and problem solving (Cleghorn et al, 1991). However, in a study comparing schizophrenia patients with (n=26) and without (n=37) cannabis use 10-12 years after the admission for a first-episode of psychosis, Stirling et al (2005) reported that cannabis users had better cognitive functioning than patients without cannabis use in several domains including design memory, verbal fluency, object assembly, block design, picture completion, picture arrangement, and face recognition memory.…”
Section: Discussionsupporting
confidence: 93%
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“…Our results are in agreement with a previous study showing no differences between schizophrenia patients with (n=38) and without (n=25) a history of cannabis abuse for performance at tests assessing intelligence, memory, learning, fluency, and problem solving (Cleghorn et al, 1991). However, in a study comparing schizophrenia patients with (n=26) and without (n=37) cannabis use 10-12 years after the admission for a first-episode of psychosis, Stirling et al (2005) reported that cannabis users had better cognitive functioning than patients without cannabis use in several domains including design memory, verbal fluency, object assembly, block design, picture completion, picture arrangement, and face recognition memory.…”
Section: Discussionsupporting
confidence: 93%
“…In contrast, several studies have compared schizophrenia patients with and without substance use disorders with regard to cognitive functions dependent on the dorsolateral prefrontocortical region. Studies have reported some cognitive deficits in cocaine (Sevy et al, 1990;Serper et al, 2000) and alcohol (Allen et al, 1999;Bowie et al, 2005) abusers compared to non-substance users, but other studies did not find cognitive differences between substance abusers and non-substance users (Cleghorn et al, 1991;Nixon et al, 1996;Addington and Addington, 1997;Pencer and Addington, 2003). Discrepancies between studies in schizophrenia patients abusing alcohol may be age related, with cognitive deficits becoming more apparent in older patients abusing alcohol (Allen et al, 1999;Bowie et al, 2005).…”
Section: Introductionmentioning
confidence: 99%
“…Aducen que sólo tendría sentido postulando la necesidad de una personalidad premórbida para la esquizofrenia, concepto que ha ido perdiendo adeptos en las últimas décadas. Si los cannabistas tienden a presentar síntomas positivos de esquizofrenia y además de aparición aguda (Cleghorn et al, 1991;Knudsen y Vilmar, 1984;Negrete et al, 1986;Treffert, 1978;Weil, 1970), entonces no cabe pensar en una fase prodrómica tan importante y dilatada como para permitir instaurarse un cannabismo duradero y causar así esquizofrenia, por intenso que haya sido el consumo (Allebeck et al, 1993). A menos que se aduzca una personalidad premórbida de muy prolongada latencia, difícil de demostrar.…”
Section: ¿El Cánnabis Produce Esquizofrenia?unclassified
“…Desde el punto de vista sintomatológico (Linszen et al, 1994), los estudios sobre cánnabis y esquizofrenia concuerdan en tres importantes hallazgos: 1) que al consumirse cánnabis hay incremento de síntomas psicóticos positivos, siendo este incremento dosisdependiente (Cleghorn et al, 1991;Knudsen y Vilmar, 1984;Negrete et al, 1986;Treffert, 1978;Weil, 1970);…”
Section: ¿El Cánnabis Produce Esquizofrenia?unclassified
“…Two recent metaanalyses concluded that cannabis use confers an overall two-fold increase in the relative risk for later schizophrenia, depending on age of onset and frequency of cannabis use (Arseneault et al, 2004;Henquet et al, 2005a). If schizophrenia occurs, cannabis-using patients seem to be prone to develop more severe positive symptoms, to suffer a more continuous course of disorder and more frequent relapses (Caspari, 1999;Cleghorn et al, 1991;D'Souza et al, 2005;Grech et al, 2005;Johns, 2001). …”
Section: Introductionmentioning
confidence: 99%