Substance Misuse Decreases Heart Rate Variability

Abstract

There are few biomarkers to reflect the physiological conditions for substance misuse. In this study, autonomic nervous and cardiovascular parameters were measured for participants in deferred prosecution programs. The goal of this study is to develop significant biomarkers of the above subjects and enhance their motivation to join further substance misuse disorder treatment program. This study recruited 34 participants with a mean age of 35.1 years. The participants spent approximately five minutes filling in the basic information form and another five minutes filling in the Pittsburgh Sleep Quality Index (PSQI). Blood pressure, heart rate, and heart rate variability data were also measured. Their sleep quality was measured by the Pittsburgh Sleep Quality Inventory (PSQI) with an average score of 8.6 and average systolic and diastolic pressure measured of 116.1 ( standard deviation SD = 13.7 ) and 77.9 mmHg ( SD = 8.1 ) during resting, respectively. Average heartbeat rates are 90.4 beats per minute ( SD = 17.0 ); and average low-frequency power ratio is 56.4% ( SD = 19.8 %). Of the participants, 35% exhibited a low-frequency power rate below 30% and above 70%. The average biological HRV age of the participants was 46.0 years ( SD = 22.9 ), which was significantly older than their average actual age ( p = 0.002 ∗ ∗ ). The biological HRV age of the participants is 10 years older than their own actual age, and it effectively reflects the physiological conditions of participants in deferred prosecution programs. These physiological parameters, especially the biological HRV age, can be used in future treatment for substance use disorder counseling programs to increase the illness insight of program participants and increase their motivation to join further substance misuse disorder treatment program.

Phenotyping the autonomic nervous system in pregnancy using remote sensors: potential for complication prediction

“…Due to its complex task, the ANS has various relationships with internal and external elements. For example, age (Jandackova et al, 2016;Geovanini et al, 2020), prenatal alcohol consumption (Karpyak et al, 2014;Jurczyk et al, 2019), smoking (Harte et al, 2013;Bodin et al, 2017;Murgia et al, 2019), drug use (Nayak et al, 2020;Lu et al, 2022;Qiu et al, 2023), and BMI (Rodrigues and Quarto, 2018;Triggiani et al, 2019) have been shown to have a correlation with HRV. Although demographic factors such as age cannot be controlled, other factors that are mainly lifestyle-related factors are adjustable by the individual.…”

“…On the other hand, for the aforementioned adverse pregnancy outcomes, evidence has identified several sociodemographic and medical history factors as potential risk factors, which are also associated with ANS dysfunction. These include age (Jandackova et al, 2016;Geovanini et al, 2020), prenatal alcohol consumption (Karpyak et al, 2014;Jurczyk et al, 2019), smoking (Harte et al, 2013;Bodin et al, 2017;Murgia et al, 2019), drug use (Nayak et al, 2020;Lu et al, 2022;Qiu et al, 2023), and body mass index (BMI) (Rodrigues and Quarto, 2018;Triggiani et al, 2019). Due to the associations between the aforementioned risk factors and pregnancy complications and ANS dysfunction, it seems that the ANS may explain the pathway between the risk factors and the pregnancy outcomes, which already indicated in ANS dysfunction (or maybe correctional but not optimal adaptation) in response to the risk factors resulting in pregnancy complications.…”

Heart Rate Variability Parameters Were Not Associated With 30-Day All-Cause Mortality in Intensive Care Unit Patients With or Without Atrial Fibrillation: A Retrospective Study of the Mimic-Iv Database

“…The underlying causes for the lack of difference in time-domain variables between survivors and nonsurvivors without AF could be explained by several hypotheses. First, because sedatives (28) and opioids (29) are thought to affect cardiac autonomic function, the lack of difference in the use of sedatives (propofol and midazolam) or opioids between both groups may partly explain this. In addition, the pain experienced by the patients, which can also affect HRV (30), may also be similar.…”

Retracted: Substance Misuse Decreases Heart Rate Variability

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”