Subtypes of Irritable Bowel Syndrome in Children: Prevalence at Diagnosis and at Follow-Up

Giannetti, Eleonora; Angelis, G.L. De; Turco, Rosa; Campanozzi, Angelo; Pensabene, Licia; Salvatore, S.; Seta, Francesco De; Staiano, Annamaria

doi:10.1016/j.jpeds.2013.12.043

Cited by 45 publications

(37 citation statements)

References 37 publications

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“…Our findings are supported by those of Giannetti et al 34 and our previous work reporting girls as more likely to have hard (type 1 or 2) stools compared with boys with IBS who had a higher prevalence of loose (type 6 or 7) stools. 19 This is similar to the adult literature, which notes men reporting more diarrhea symptoms than women.…”

Section: Discussionsupporting

confidence: 92%

Childhood Irritable Bowel Syndrome Characteristics Are Related to Both Sex and Pubertal Development

Chumpitazi

Weidler

Czyzewski

et al. 2017

The Journal of Pediatrics

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Objective To determine the relationship of both pubertal development and sex to childhood irritable bowel syndrome (IBS) clinical characteristics including gastrointestinal symptoms (eg, abdominal pain) and psychological factors. Study design Cross-sectional study with children ages 7–17 years (n = 143) with a pediatric Rome III IBS diagnosis recruited from both primary and tertiary clinics between January 2009 and January 2014. Subjects completed 14-day prospective pain and stool diaries, as well as validated questionnaires assessing several psychological factors (somatization, depression, anxiety) and Tanner stage. Stool form ratings were completed using the Bristol Stool Form Scale. Results Girls with higher Tanner scores (more mature pubertal development) had both decreased pain severity and pain interference; in contrast, boys with higher Tanner scores had both increasing pain severity (β = 0.40, P = .02) and pain interference (β = 0.16, P = .02). Girls (vs boys), irrespective of pubertal status, had both increased somatic complaints (P = .005) and a higher percentage (P = .01) of hard (Bristol Stool Form Scale type 1 or 2) stools. Pubertal status and sex did not significantly relate to IBS subtype, pain frequency, stooling frequency, anxiety, or depression. Conclusions In children with IBS, both pubertal development and/or sex are associated with abdominal pain severity, stool form, and somatization. These differences provide insight into the role of pubertal maturation during the transition from childhood to adult IBS.

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Section: Discussionsupporting

confidence: 92%

Childhood Irritable Bowel Syndrome Characteristics Are Related to Both Sex and Pubertal Development

Chumpitazi

Weidler

Czyzewski

et al. 2017

The Journal of Pediatrics

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“…In addition, the subcommittee has polled authors of studies on pediatric IBS‐C to obtain information on the number of daily bowel movements in children with this diagnosis. Data from two studies have shown that the mean number of bowel movements was variable among children with IBS‐C with a wide spectrum that ranged from one to seven BMs a week . These results are in agreement with a published study on IBS‐subtypes in children that showed that the majority of children with IBS‐C had >3 bowel movements weekly with 48% of children having one or more bowel movements daily .…”

Section: Commentssupporting

confidence: 86%

Recommendations for pharmacological clinical trials in children with irritable bowel syndrome: the Rome foundation pediatric subcommittee on clinical trials

Saps

Tilburg

Lavigne

et al. 2016

Neurogastroenterology Motil

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The subcommittee recommends randomized, double-blind, placebo-controlled, parallel-group, clinical trials to assess the efficacy of new drugs. The combined endpoints for abdominal pain are a decrease in intensity of at least 30% compared with baseline and to meet or exceed the Reliable Change Index (RCI) for the sample. Stool consistency is measured with the Bristol Stool Scale Form (BSFS). The subcommittee recommends as entry criteria for abdominal pain a weekly average of worst abdominal pain in past 24 h of at least 3.0 on a 0-10 point scale or at least 30 mm in 100 mm Visual Analog Scale. For stool endpoints the committee recommends an average stool consistency lower than 3 in the BSFS during the run-in period for clinical trials on IBS-C and an average stool consistency greater than 5 in the BSFS during the run-in period for clinical trials on IBS-D. Changes in stool consistency are the primary endpoints for both IBS with diarrhea (IBS-D) and IBS with constipation (IBS-C).

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“…Hubungan pendidikan orangtua yang rendah berbanding terbalik dengan faktor risiko terjadinya IBS berkaitan dengan ketersediaan nutrisi dan pelayanan kesehatan, serta kualitas lingkungan sehat. [17][18][19][20][21][22] Status ekonomi tidak mempunyai hubungan dengan IBS. Sementara di Korea didapatkan bahwa status ekonomi berhubungan dengan IBS.…”

Section: Metodeunclassified

Hubungan Masalah Perilaku pada Remaja dengan Irritable Bowel Syndrome

Kesuma¹

2017

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Latar belakang. Irritable bowel syndrome (IBS) merupakan nyeri perut berulang pada remaja yang paling banyak terjadi. Oleh karena itu, IBS akan menimbulkan gangguan perilaku yang serius pada remaja. Tujuan. Menganalisis hubungan antara masalah perilaku dengan IBS pada remaja. Metode. Penelitian potong lintang semua siswa SMA Nurul Iman. Pencatatan dilakukan meliputi karakteristik umum dan pemeriksaan fisis. Selanjutnya dilakukan uji Rome III (irritable bowel syndrome) dan PSC-17 (masalah perilaku). Analisis statistik digunakan analisis bivariat dengan uji chi-square. Hasil. Dari siswa SMA Nurul Iman didapatkan 180 subyek yang memenuhi kriteria inklusi dan tidak memenuhi kriteria eksklusi. Prevalensi IBS 58 (32,2%) subyek, terdiri atas 22 subtipe konstipasi, 23 subtipe diare, dan 13 subtipe campuran. Prevalensi masalah perilaku 40,6%, terdiri atas 28,9% masalah perilaku internalisasi, 2,8% masalah eksternalisasi, 0,6% masalah perilaku perhatian, dan 8,4% variasi dari 3 gangguan. Faktor risiko terjadinya IBS, antara lain, mengonsumsi daging olahan, teh, makan terburu-buru, serta di-bully. Terdapat hubungan yang bermakna antara IBS dengan masalah perilaku (p=0,001). Nilai Odds Ratio yang diberikan 3,015 (IK95%=1,580-5,754) Kesimpulan. Remaja yang mengalami IBS mempunyai risiko yang meningkat untuk terjadinya masalah perilaku. Sari Pediatri 2017;18(6):492-7Kata kunci: masalah perilaku, irritable bowel syndrome, remaja Association between Behavioral Problems among Irritable Bowel Syndrome Adolescents Yudianita KesumaBackground. Irritable bowel syndrome (IBS) is the most common recurrent abdominal pain in adolescence, causing serious impairments on behavioral problems. Objective. To assess for an association between IBS and behavioral problems in adolescences. Methods. Subjects in this cross-sectional study were adolescences who attended Nurul Iman high school. Their general characteristics and physical examination results were recorded. We administered the Criteria Rome III for IBS and the Pediatric Symptom Checklist 17 (PSC 17) for behavioral problems. Data was analyzed by Chi-square test. Results. We enrolled 180 adolescences as student in Nurul Iman high school. Prevalences of IBS was 32,2%, consisting of subtype IBS constipation (37,9%), subtype IBS Diarrhea (39,7%), and subtype IBS Mixed (22,4%). The prevalence of behavioral disorders was 40,6%, consisting of internalization (28,9%), externalization (2,8%), attentive problems (0,6%) and various combinations of three problems (8,4%). A significant association was found between IBS and behavioral problems (P=0.001; PR=3.015; 95%CI=1.580-5.754). Conclusion. IBS is significantly associated with behavioral problems. Sari Pediatri 2017;18(6):492-7

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Subtypes of Irritable Bowel Syndrome in Children: Prevalence at Diagnosis and at Follow-Up

Cited by 45 publications

References 37 publications

Childhood Irritable Bowel Syndrome Characteristics Are Related to Both Sex and Pubertal Development

Childhood Irritable Bowel Syndrome Characteristics Are Related to Both Sex and Pubertal Development

Recommendations for pharmacological clinical trials in children with irritable bowel syndrome: the Rome foundation pediatric subcommittee on clinical trials

Hubungan Masalah Perilaku pada Remaja dengan Irritable Bowel Syndrome

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