Successful conservative management of primary nonmetastatic cervical choriocarcinoma

Primary cervical choriocarcinoma: report of four cases and literature review

“…Gestational choriocarcinoma usually occurs in the uterine corpus but because of placental implantation, it rarely occurs in the cervix. There are approximately 82 case reports of cervical choriocarcinoma in the literature (1–11) (see Table 1).…”

“…Occasionally, diagnosis of cervical choriocarcinoma is also difficult for pathologists both in biopsy and in surgical specimen. The cells of cervical squamous carcinoma may have abundant eosinophilic cytoplasm as seen in cytotrophoblasts and may have more than one nucleus, thus resembling syncytiotrophoblast (7) . It is not surprising therefore that an invasive squamous carcinoma of the cervix has been diagnosed based on biopsy in their case by Ben‐Chetrit et al (7) .…”

“…Gestational choriocarcinoma most commonly arises within the uterine corpus and rarely in the cervix. There are approximately 82 case reports of cervical choriocarcinoma in the literature including Chinese that cannot be searched by PubMed (1–11) (see Table 1). In this report, we present additional four cases of cervical choriocarcinoma diagnosed in our department from January 1987 to January 2005.…”

Primary Cervical Choriocarcinoma: Case Report and the Review of Literatures

“…In our case, the first pathologist misdiagnosed choriocarcinoma with squamous cell carcinoma as Ben-Chetrit [18]. Necrosis is a predominant feature of these neoplasms, often to such an extent that the viable tissue is obscured.…”

“…Interestingly, Ben-Chetrit and his co-workers in one report and Roopnarinesingh et al in other report, documented conservative management of primary cervical choriocarcinoma [4,18].…”