Successful Liver Transplantation from a Living Donor to Her Son

Strong, Russell W.; Lynch, Stephen V.; Ong, T. H.; Matsunami, Hidetoshi; Koido, Yuichi; Balderson, Glenda A.

doi:10.1056/nejm199005243222106

Cited by 750 publications

(330 citation statements)

References 8 publications

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“…These techniques could be applied to cadaver donors in the performance of SLT (11,12) or to live volunteers to create living-donor liver transplantation (13,14).…”

Section: Historic Backgroundmentioning

confidence: 99%

Split-Liver Transplantation: A Review

Renz

Yersiz

Reichert

et al. 2003

American Journal of Transplantation

104

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Split-liver transplantation (SLT), a procedure where one cadaver liver is divided to provide for two recipients, offers immediate expansion of the existing cadaver donor pool. To date, the principal beneficiaries of SLT have been adult/pediatric recipient pairs with excellent outcomes reported; however, the current scarcity of cadaver organs has renewed interest in expanding these techniques to include two adult recipients from one adult cadaver donor. Significant obstacles to the widespread application of SLT exist and must be resolved by the transplant community before greater utilization can be realized. This manuscript reviews the historic background, surgical techniques, current results, and obstacles impeding further application of SLT.

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“…These techniques could be applied to cadaver donors in the performance of SLT (11,12) or to live volunteers to create living-donor liver transplantation (13,14).…”

Section: Historic Backgroundmentioning

confidence: 99%

Split-Liver Transplantation: A Review

Renz

Yersiz

Reichert

et al. 2003

American Journal of Transplantation

104

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“…Both transplant recipients died soon after the procedure. This was followed by the report of Strong et al 2 in Australia, where the first successful transplantation in a child using its mother's left lobe was performed in July 1989. The first successful LRLT for an adult patient was reported by Hashikura et al 3 at Shinshu University.…”

mentioning

confidence: 99%

Safe donor hepatectomy for living related liver transplantation

Sugawara

Makuuchi

Takayama

et al. 2002

Liver Transplantation

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Minimizing the risk of donor hepatectomy while preserving graft viability is an important concern in living related liver transplantation. This report describes clinical outcomes for living donor hepatectomy with reference to the type of hepatectomy. Donor hepatectomy was performed in 130 consecutive living donors. They were divided into three groups: left lateral or extended left lateral segmentectomy (group S; n ‫؍‬ 50), left hepatectomy with or without caudate lobe or right lateral resection (group L; n ‫؍‬ 64), and right hepatectomy (group R; n ‫؍‬ 16). Intraoperative and postoperative data were examined and compared among the groups. No critical complications were observed in any group. However, there were differences in donor age, surgical and ischemia times, volume of blood loss, graft weight, and aspartate aminotransferase level elevation among the groups. Livers showed a substantial increase in volume, tending to the standard liver volume 1 month after surgery. Regardless of the extent of donor hepatectomy, serious complications did not occur after surgery. Surgical risk for a living donor is minimal if the operation is performed by experienced surgeons using present procedures. (Liver Transpl 2002;8:58-62.)

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“…Living donor liver transplantation from an adult liver to a child was first done successfully by Strong and Lynch in Adelaide, Australia. 49 The operation for pediatric recipients was subsequently popularized by Christoph Broelsch and associates at the University of Chicago,SO who reported their results at the American Surgical Association conference in 1990 along with their experience with reduced-size deceased-donor organs and deceased-donor split livers.…”

Section: Living Donor Transplantationmentioning

confidence: 99%