Successful Management of Choriocarcinoma with pregnancy

Abstract

CORRESPONDENCE gathered from the treatment of osteosarcomas of the bone. The recommendation of combination chemotherapy in these tumors is further supported by available data on extraosseous osteogenic sarcomas in locations other than the breast (19). Of 8 patients, 3 women who were not treated with chemotherapy died within 25 months of tumor progression, whereas among the remaining 5 patients treated with chemotherapy in the course of the disease, one patient was followed up for 12 months without evidence of disease and 2 patients survived for 76 months each. As in primary sarcoma of the breast, the lung, followed by the liver, were the preferential sites of metastasis. Research on preoperative chemotherapy of primary osteosarcoma of the bone to reduce tumor volume and avoid amputation has increased in recent years (20). However, this regimen cannot be considered appropriate for primary osteosarcoma of the breast, and mastectomy still remains the surgical treatment of choice.