Background The trends observed in cancer breast among Indian women are an indication of effect of changing lifestyle in population. To draw an appropriate inference regarding the trends of a particular type of cancer in a country, it is imperative to glance at the reliable data collected by Population Based Cancer Registries over a period of time.Objective To give an insight of changing trends of breast cancer which have taken place over a period of time among women in Cancer Registries of India. Breast Cancer trends for invasive breast cancer in women in Indian Registries have varied during the selected period. Occurrence of breast cancers has also shown geographical variation in India. Materials and Methods This data was collected by means of a 'Standard Core Proforma' designed by NCRP conforming to the data fields as suggested by International norms. The Proforma was filled by trained Registry workers based on interview/ hospital medical records/ supplementing data by inputs from treating surgeons/radiation oncologists/involved physicians/pathologists. The contents of the Proforma are entered into specifically created software and transmitted electronically to the coordinating center at Bangalore. The registries contributing to more number of years of data are called as older registries, while other recently established registries are called newer registries.Results While there has been an increase recorded in breast cancer in most of the registries, some of them have recorded an insignificant increase. Comparison of Age Adjusted Rates (AARs) among Indian Registries has been carried out after which trends observed in populations covered by Indian Registries are depicted. A variation in broad age groups of females and the proneness of females developing breast cancer over the period 1982 to 2010 has been shown. Comparisons of Indian registries with International counterparts have also been carried out. Conclusions There are marked changes in incidence rates of cancer breast which have occurred in respective registries in a developing country like India. A steady increase in AARs in most of the registries of India including the newly established registries is indicative of the fact that cancer breast poses a threat to women in India.

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CORRESPONDENCE gathered from the treatment of osteosarcomas of the bone. The recommendation of combination chemotherapy in these tumors is further supported by available data on extraosseous osteogenic sarcomas in locations other than the breast (19). Of 8 patients, 3 women who were not treated with chemotherapy died within 25 months of tumor progression, whereas among the remaining 5 patients treated with chemotherapy in the course of the disease, one patient was followed up for 12 months without evidence of disease and 2 patients survived for 76 months each. As in primary sarcoma of the breast, the lung, followed by the liver, were the preferential sites of metastasis. Research on preoperative chemotherapy of primary osteosarcoma of the bone to reduce tumor volume and avoid amputation has increased in recent years (20). However, this regimen cannot be considered appropriate for primary osteosarcoma of the breast, and mastectomy still remains the surgical treatment of choice.