Successful Management of Melanocytoma-Associated Choroidal Neovascularization with Photodynamic Therapy

Abstract

Photodynamic therapy effectively resolved CNV that involved papillomacular bundle (secondary to melanocytoma) and restored retinal function in papillomacular bundle.

Test–Retest Variability of Microperimetry Using the Nidek MP1 in Patients with Macular Disease

“…The Nidek MP1 microperimeter (Nidek Technologies, Padova, Italy) has several advantages: It is user friendly, incorporates an eye tracker, allows automated follow-up examination at the same retinal loci, and is combined with a color fundus camera for image registration. 7 The popularity of this instrument is reflected by the numerous case studies, case series, and clinical trials using change in microperimetry measures to document the natural history 8 -11 or treatment responses [12][13][14][15][16][17][18][19][20][21] in various retinal and optic nerve diseases. 22 Intrinsic to any psychophysical test is measurement error or test-retest variability.…”

Melanocitoma associado à membrana neovascular sub-retiniana

“…Em um dos relatos o paciente foi submetido à remoção cirúrgica da membrana neovascular com bom resultado funcional final (6) . Chalam e colaboradores descrevem um caso tratado de maneira bem-sucedida com terapia fotodinâmica (7) . Não encontramos referência ao uso de injeção intravítrea de antiangiogênicos para tratamento da membrana associada ao melanocitoma.…”

Management of Optic Disc Melanocytoma Associated with Choroidal Neovascularisation and Macular Detachment

“…These secondary CNVMs are easily imaged by FFA and warrant prompt intervention. Previous authors have described the use of Photodynamic Therapy (PDT) [12], intravitreal pharmacotherapy with bevacizumab [14] and submacular surgery [13] for CNVM removal. In all of these patients the visual outcome encouraging, as the CNVM was managed before it caused permanent macular photoreceptor damage.…”

“…Subretinal haemorrhage and exudation will follow the occurrence of a CNVM, often causing a drastic worsening in vision. Different methods of managing CNVM in melanocytoma have been reported, ranging from photodynamic therapy to submacular surgery [12][13][14]. The discovery of anti-vascular Endothelial Growth Factor (VEGF) molecules has been a boon to the management of sight threatening intraocular neovascular processes.…”