Successful Management of Quadruplet Pregnancy following Spontaneous Conception

Shrestha, Deepak; Thapa, Badri; Aryal, Shreyashi; Shrestha, Buddhi Kumar; Panthee, Kiran; Kalakheti, Balkrishna

doi:10.22502/jlmc.v4i1.88

Cited by 5 publications

(10 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The overall prevalence of HOM pregnancy in this study was 0.2% or one in 545.5 of all deliveries. This is higher than the prevalence of 0.01%–0.07% reported by other studies, 1 , 2 , 7 but lower than 1.48% earlier reported in the United States. 3 The lower prevalence may be because all the HOM pregnancies in the earlier studies by Nnadi et al, 1 Rathod et al, 2 and Shrestha et al 7 were conceived naturally.…”

Section: Discussioncontrasting

confidence: 69%

“…This is higher than the prevalence of 0.01%–0.07% reported by other studies, 1 , 2 , 7 but lower than 1.48% earlier reported in the United States. 3 The lower prevalence may be because all the HOM pregnancies in the earlier studies by Nnadi et al, 1 Rathod et al, 2 and Shrestha et al 7 were conceived naturally. The higher prevalence reported in the United States was due to the increased use of ART for conception, compared to Abakaliki (Nigeria), where the ART procedure is still in its rudimentary stage due to the problems of affordability and acceptance among the majority of women who need it.…”

Section: Discussioncontrasting

confidence: 69%

“…Spontaneous quadruplet pregnancy is very uncommon and it is estimated to occur in 1 in 512,000 to 1 in 677,000 births. 2 , 7 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fetal and maternal outcome of higher-order multiple pregnancies in a tertiary hospital: A 5-year single-center observational study from Nigeria

et al. 2022

View full text Add to dashboard Cite

Objective: The aim of this study was to determine the pattern and outcomes of higher-order multiple pregnancies in a tertiary hospital in Nigeria Methods: This is a retrospective review of all cases of higher-order multiple pregnancies that were managed between 1 January 2012 and 31 December 2016 in Alex Ekwueme Federal University Teaching Hospital Abakaliki, Nigeria. Data obtained were represented with frequency tables, percentages, bar charts, and odds ratio. Results: There were 22 higher-order multiple pregnancies over the study period and 12,002 deliveries, giving a higher-order multiple prevalence rate of 0.2%. Five of the mothers (four triplets and one quadruplet) had in vitro fertilization (0.4 per 1000 deliveries), while other mothers conceived naturally. Many of the women (12, 54.6%) were in the 30–34 years age group, and more than half (16, 72.7%) were multiparas. More than half of the neonates were delivered preterm (13, 59.1%). Being booked is associated with better neonatal outcomes although not significant (odds ratio = 3.06. 95% confidence interval: 0.55–16.83, p = 0.197). Anemia was common in the antepartum and postpartum periods. Half of the women (11, 50%) were delivered by elective cesarean section and 7 (31.8%) by emergency cesarean section (C/S), while 4 (18.2%) had a spontaneous vaginal delivery. The neonates had a mean birth weight of 2.14 ± 0.35 kg. Overall, 61 neonates (91.0%) were born alive and 6 (9.0%) suffered perinatal deaths, giving a perinatal mortality rate of 89.8 neonates per 1000 live births. Conclusion: Our study shows that higher-order multiple pregnancies are high-risk pregnancies that are associated with fetal and maternal complications. Anemia is the commonest complication seen in our study. The majority had preterm delivery. Proper antenatal care and close feto-maternal monitoring are important in reducing adverse outcomes associated with these pregnancies.

show abstract

Section: Discussioncontrasting

confidence: 69%

Section: Discussioncontrasting

confidence: 69%

See 1 more Smart Citation

Fetal and maternal outcome of higher-order multiple pregnancies in a tertiary hospital: A 5-year single-center observational study from Nigeria

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In the literature, cases of spontaneous quintuplet pregnancies have been reported in India, Pakistan, and Germany [3] , [6] . Many cases of quintuplet pregnancies have been obtained after embryo transfer following in vitro fertilization [4] , [7] , [9] .…”

Section: Introductionmentioning

confidence: 99%

First recorded spontaneous quintuplets born in Somalia: A case report

Hussein¹

2021

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

Introduction and importance Quintuplets conceived spontaneously are a rare occurrence. As compared with singleton pregnancies, quintuplets are associated with high rates of obstetric complications and significant prenatal morbidity and mortality. To our knowledge, here we reported the first case of spontaneous quintuplet pregnancy faced by a practicing clinician in an underdeveloped country (Somalia) with a Successful outcome. Case presentation A 32-year-old woman presented in her third trimester of gestation at 30 weeks feeling pain and uterine contractions. Clinical findings and investigations Ultrasound examination showed multiple pregnancies with four alive intrauterine pregnancies, but quintuplets could not be ruled out. Fetal heart activities were present, and the amniotic fluid was normal in amount. Interventions and outcome Extensive preparations made included four sets of ventilators. We did an emergency cesarean section under spinal anesthesia: five alive infants, three boys and two girls delivered in cephalic and breech presentations. Conclusions Quintuplet pregnancy is rare but poses relevant clinical problems to both the obstetrician and the neonatologist. Relevance and impact The takeaway lesson from this case would be that Pregnancy with multiples is considered a high-risk pregnancy; with more complications observed as the number of fetuses increases, their effective follow-up requires early diagnosis with regular monitoring. Through this case, we would like to highlight the urgent need to focus on the delivery of women's health care services in Somalia, along with the need to recognize the importance of receiving antenatal care in the community so that the burden of thousands of lives that are lost each year could be reduced. This case report has been reported according to the SCARE Criteria (Agha et al., 2020).

show abstract

“…Assisted Reproductive Technologies have contributed significantly to increase in the incidence of multiple pregnancies around the word. The risk of perinatal mortality and morbidity is high and often linked to prematurity [1] [3] [4]. This situation is sometimes a difficult problem for parents and obstetricians with the use of reduction techniques to improve the fetal and maternal prognosis [5] [6].…”

mentioning

confidence: 99%

Quintuplet Pregnancy: A Rare Case after Clomiphene Citrate Therapy and Review of Literature

Bambara¹,

Issa²,

Barnabé³

et al. 2019

OJOG

View full text Add to dashboard Cite

Multiple pregnancies are increasing with the progress in Assisted Reproductive Technology. The authors report a case of quintuplet pregnancy after Clomiphene Citrate stimulation. This is a 28-year-old woman, G2, P1 with a 4-year-old child alive, who consulted for maternity desire. She was treated with Clomiphene Citrate at 100 mg daily for five days. The presence of a quintuplet pregnancy at 8 weeks + 5 days was found by ultrasound on 29/12/2018. During the follow up of the pregnancy, she presented pre-eclampsia from 24 th week (TA 140/100 mmHg, significant proteinuria, edema of lower limbs). Methyl Dopa treatment was instituted. Tocolytic treatment with Salbumol was prescribed facing uterine contractions at 30 weeks. The patient had premature rupture of membranes at 34 weeks + 4 days, followed by uterine contractions. She had a cesarean section at the same day with the birth of five newborns alive. This is the first reported case in Burkina Faso.

show abstract

Successful Management of Quadruplet Pregnancy following Spontaneous Conception

Cited by 5 publications

References 9 publications

Fetal and maternal outcome of higher-order multiple pregnancies in a tertiary hospital: A 5-year single-center observational study from Nigeria

Fetal and maternal outcome of higher-order multiple pregnancies in a tertiary hospital: A 5-year single-center observational study from Nigeria

First recorded spontaneous quintuplets born in Somalia: A case report

Quintuplet Pregnancy: A Rare Case after Clomiphene Citrate Therapy and Review of Literature

Contact Info

Product

Resources

About