Successful pregnancy outcome in Swyer-James-Macleod syndrome

Abstract

Swyer-James-MacLeod (SJM) syndrome is a chronic, progressive lung disease as a result of infection and bronchial obstruction that ultimately leads to emphysema. It is associated with chronic cough, sputum production and recurrent chest infections and is occasionally seen in women of reproductive age. The radiological finding of unilateral hyperlucent lung is considered synonymous with the disease entity.

Swyer-James-MacLeod syndrome in pregnancy: A case report

“…The incidence of SJMS in pregnancy is estimated at 1:2500. 4 There is a paucity of literature on SJMS in pregnancy with only one other available case report. 4 That woman was 30 years old with posttuberculosis SJMS who similarly had moderate obstructive lung disease.…”

“…4 There is a paucity of literature on SJMS in pregnancy with only one other available case report. 4 That woman was 30 years old with posttuberculosis SJMS who similarly had moderate obstructive lung disease. Her pregnancy was complicated by pre-eclampsia requiring delivery at 34 weeks of gestation.…”

A persistent pneumothorax? 5-year follow-up after diagnosis of Swyer–James–MacLeod syndrome

“…Swyer–James–MacLeod syndrome is often diagnosed in childhood and the long-term clinical course of Swyer–James–MacLeod syndrome in adults has not been well described. There are isolated case reports and small case series describing the diagnosis of Swyer–James–MacLeod syndrome in adults [ 4 – 9 ]. One case series describes the first diagnosis of Swyer–James–MacLeod syndrome in four patients aged 33–51 years [ 4 ].…”

“…Although our patient has no signs or symptoms of pulmonary hypertension, we decided to monitor her with yearly echocardiography. Reports on long-term follow-up and prognosis of Swyer–James–MacLeod syndrome are lacking in the literature; however, one case report describes a normal pregnancy outcome in a patient with the condition [ 9 ].…”

Cases Diagnosed with Swyer James Macleod Syndrome in Adulthood

“…There is hypoplasia in the vascular structures and hyperinflation and panacinar emphysematous changes occur in the distal aspect of the involved bronchiole. Loss of ciliary motility enhances tendency to secondary infections [6,7]. As the consequence, it has been demonstrated that cases with SJMS histopathologically develop emphysema, cystic cavities that indicate cystic bronchiectasis, interstitial chronic inflammatory changes, bronchial lymphatic tissue hyperplasia, diffuse obliteration in the pulmonary capillary bed, pulmonary arterial hypertrophy, bronchitis, bronchiolitis, peribronchial fibrosis, and smooth muscle proliferation [8].…”