Successful Treatment of a Large Solitary Nasal Tip Trichoepithelioma Using the 10,600-nm Carbon Dioxide Laser

Yong, Angeline Anning; Goh, C. J.

doi:10.1097/dss.0000000000000321

Cited by 1 publication

(4 citation statements)

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“…17,21 In addition, the use of carbon dioxide laser in this setting has been associated with high levels of satisfaction and low levels of recurrence. 17,20,21,31,32 In other reports, carbon dioxide laser, particularly in continuous wave mode, has achieved only partial clearance of lesions with gradual recurrence over time as well as the appearance of new lesions. 33 Multiple laser passes are required when treating trichoepithelioma because of high tissue density, making ablation more challenging.…”

Section: Imiquimod and Carbon Dioxide Lasermentioning

confidence: 99%

“…Treatment of multiple trichoepithelioma with carbon dioxide laser has been reported to have acceptable cosmetic results, minimising the appearance of lesions without causing a considerable amount of pain, bleeding and postsurgical oedema 17,21 . In addition, the use of carbon dioxide laser in this setting has been associated with high levels of satisfaction and low levels of recurrence 17,20,21,31,32 . In other reports, carbon dioxide laser, particularly in continuous wave mode, has achieved only partial clearance of lesions with gradual recurrence over time as well as the appearance of new lesions 33 .…”

Section: Pharmacological Therapiesmentioning

confidence: 99%

“…17,18 Laser treatments can be safe and effective, achieving acceptable cosmetic outcomes and significant lesion clearance in majority of cases with no recurrence and minimal morbidity. 19,20 Furthermore, being minimally invasive, laser treatments may reduce the incidence of complications associated with surgical techniques. 19 Commonly reported complications of treatment with laser include hypertrophic scarring, prolonged recovery time, oozing, oedema, erythema, ulceration, burning sensation, risk of post-inflammatory hyperpigmentation or hypopigmentation, and incomplete resolution of lesions.…”

Section: Introductionmentioning

confidence: 99%

“…The advantages of ablative laser include the rapid removal of large numbers of lesions 17,18 . Laser treatments can be safe and effective, achieving acceptable cosmetic outcomes and significant lesion clearance in majority of cases with no recurrence and minimal morbidity 19,20 . Furthermore, being minimally invasive, laser treatments may reduce the incidence of complications associated with surgical techniques 19 .…”

Section: Introductionmentioning

confidence: 99%

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Management of multiple trichoepithelioma: A review of pharmacological therapies

2021

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Trichoepithelioma is a rare benign adnexal neoplasm that can occur in various forms including solitary, multiple, familial or nonfamilial. Multiple facial trichoepithelioma can be associated with significant psychosocial burden. Conventional treatment modalities such as surgical excision and ablative laser have variable results and can be associated with unacceptable complications and tumour regrowth. Pharmacological interventions such as topical and systemic agents are potentially effective but clinical data are limited and treatments are poorly standardised. We review the available evidence to determine the role of pharmacological therapies in the management of multiple trichoepithelioma. Demographic and clinical data were retrospectively collected from the available English literature. Majority of cases treated with pharmacological therapies (93.75%) had a positive treatment outcome, achieving partial lesion response. Adverse effects associated with pharmacological therapies were generally well tolerated and did not interrupt treatment. There are limitations as to how our results can be interpreted owing to the paucity of good quality evidence, spectrum of disease severity, and diversity of study designs utilised in the included articles. Nonetheless, the results of our study indicate that while most pharmacological interventions for multiple trichoepithelioma produce a partial response, they can be employed as effective suppressive therapies, either alone or in conjunction with conventional treatments. The current evidence for pharmacological therapies remains largely anecdotal justifying the need for further clinical studies in this area.

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