Successful treatment of Aerococcus viridans endocarditis in a patient allergic to penicillin

Chen, Liang Yu; Yu, Wen Chung; Huang, Suang Hao; Lin, Michael C.; Chen, Te Li; Fung, Chang Phone; Liu, Cheng Yi

doi:10.1016/j.jmii.2011.09.010

Cited by 19 publications

(19 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This organism is generally saprophytic and has rarely been encountered as a human pathogen [4–6]. There are case reports of urinary tract infection with bacteremia and endocarditis caused by Aerococcus viridans [7, 8]. Since Aerococcus viridans is usually recognized as susceptible to penicillin, the treatment protocol for aerococcal infection is generally started with penicillin or its derivates [9].…”

Section: Discussionmentioning

confidence: 99%

<i>Aerococcus viridans</i> infection presenting as cutaneous vasculitis in an immunocompetent patient

Parrey¹,

Sofi²,

Ahmad³

et al. 2016

Reumatologia

View full text Add to dashboard Cite

BackgroundAerococcus viridans organisms are Gram-positive cocci that are widely distributed in hospital environments and room air. These bacteria have infrequently been encountered as human pathogens causing bacteremia, endocarditis and urinary tract infections. The significance of these bacteria may be overlooked due to their fastidious growth, and they are often confused with other strains of streptococci or staphylococci.Case reportWe present a case of Aerococcus viridans manifesting as cutaneous vasculitis in an immunocompetent patient. A 30-year-old female patient was admitted to hospital after two weeks history of fever, chills and papular rash over the limbs and trunk. The clinical diagnosis of vasculitis was made. Investigations revealed elevated leucocytosis (21.7 × 109/l) with 81% of neutrophils, and an elevated erythrocyte sedimentation rate or 60 mm/h. Serum anti-neutrophil cytoplasmic antibodies (ANCAs) were not found. Blood culture showed growth of Aerococcus viridans. Histopathological assessment of skin biopsy revealed cutaneous vasculitis.ConclusionsTo date, no clinical case report of this kind has been reported implicating Aerococcus viridans in cutaneous vasculitis. Increased awareness and more studies of this genus should lead to the identification of its potential role in human infections.

show abstract

Section: Discussionmentioning

confidence: 99%

<i>Aerococcus viridans</i> infection presenting as cutaneous vasculitis in an immunocompetent patient

Parrey¹,

Sofi²,

Ahmad³

et al. 2016

Reumatologia

View full text Add to dashboard Cite

show abstract

“…6,7 A. viridans causes meningitis, urinary system infection, osteomyelitis, septic arthritis, wound site infection, and more frequently bacteremia and infective endocarditis in immunocompromised patients. 8 Granulocytopenia, oral mucositis, history for long-term hospitalization, previous antibiotic use, invasive procedures, and implantations have been defined as primary risk factors for A. viridans related systemic infections. 2,6,7 Although source of contamination could not be clearly determined in the present case, we can say that it is a health-carerelated infection and comorbid immunosuppressive disease have contributed to this infection since he has been receiving hemodialysis for 6 years and had undergone invasive procedure short time ago.…”

Section: Discussionmentioning

confidence: 99%

Infective Endocarditis Caused by Multidrug-Resistant Aerococcus viridans: Case Report

Kurşun¹,

Turunç²,

Demıroğlu³

et al. 2015

Turkiye Klinikleri J Case Rep

View full text Add to dashboard Cite

“…Among the 30 strains of Aerococcus, Aerococcus viridans (83.3%) was mainly involved in the cellulitis of dental origin. The normal habitat of Aerococcus viridans is the natural environment [13]. However, in humans, it can be isolated from blood cultures (e.g.…”

Section: Susceptibility Of the Isolated Bacteria N (%)mentioning

confidence: 99%

“…A study in Tunisia noted involvement of Enterococcus in oral infections [14]. These bacteria are opportunistic pathogens, and they have been implicated in severe infections in immunocompromised as well as immunocompetent patients [13].…”

Section: Susceptibility Of the Isolated Bacteria N (%)mentioning

confidence: 99%

Occurrence and Antibiotic Susceptibility of Aerococcus and Enterococcus Strains Isolated from Acute and Chronic Cellulites of Dental Origin in Ouagadougou, Burkina Faso

WAD¹,

Konaté²,

Dembélé³

et al. 2016

Journal of Dentistry and Oral Care Medicine

View full text Add to dashboard Cite

Cellulites of dental origin are extensive polymicrobial infections of the face and neck cell-adipose tissues. Management of infections of this nature presents significant challenges. The key to this is the identification of the causative organisms and determination of their susceptibility to antibiotics. Enterococcus and Aerococcus are pathogenic and opportunistic bacteria. Despite their low virulence, these microorganisms are responsible for many human infections. A major problem with these bacteria is their frequent multidrug resistance. The lack of data on these bacterial strains involved in the cellulite in Burkina Faso thus justifies the choice of Enterococcus and Aerococcus. This study was therefore undertaken to determine bacterial etiologies and antibiotic resistance profiles associated with cellulites cases in Ouagadougou, Burkina Faso. A total of 62 samples from patients were analyzed. The isolates were obtained using conventional microbiology procedures. Strains were identified by using API 20 Strep (bioMérieux, France). Antibiotic susceptibility and detection of extended spectrum β-lactamases (ESBLs) were performed according to the European Committee of Antimicrobial Susceptibility Testing (EUCAST). The patients were 41.9% males and 58.1% females. Aerococcus was isolated from 30 patients and Enterococcus from 7. Aerococcus strains were resistant to metronidazole (100%), cefixim (93.3%), trimethoprim-sulfamethoxazole (86.7 %), oxacillin (83.3%), penicillin G (83.3%), cefotaxime (80%), chloramphenicol (80%), cefuroxime (76.7%) and to ceftriaxone (76.7%). Enterococcus strains were resistant to metronidazole (100%), cefixim (100%), cefotaxim (100%), ceftriaxone (100%), cefuroxime (100%), trimethoprim-sulfamethoxazole (100%), penicillin G (100%), oxacillin (100%) and to amoxicillin (100%). Only one Aerococcus viridans strain was positive for ESBL production (2.7%). The emergence of resistance among the bacterial strains that have been implicated in odontogenic infections is a public health issue in Burkina Faso that warrants a significant degree of concern.

show abstract

Successful treatment of Aerococcus viridans endocarditis in a patient allergic to penicillin

Abstract: Aerococcus viridans is a rare human pathogen that occasionally causes endocarditis. Most of the reported cases of endocarditis have been treated with penicillin. Here we describe a patient who was allergic to penicillin and was successfully treated with cefotaxime.

Cited by 19 publications

References 10 publications

<i>Aerococcus viridans</i> infection presenting as cutaneous vasculitis in an immunocompetent patient

<i>Aerococcus viridans</i> infection presenting as cutaneous vasculitis in an immunocompetent patient

Infective Endocarditis Caused by Multidrug-Resistant Aerococcus viridans: Case Report

Occurrence and Antibiotic Susceptibility of Aerococcus and Enterococcus Strains Isolated from Acute and Chronic Cellulites of Dental Origin in Ouagadougou, Burkina Faso

Contact Info

Product

Resources

About