Successful treatment of peritoneal dialysis catheter exit-site granuloma with silver ion-based dressing

Matinfar, Mohammad; Taheri, Shahram; Karimi, Shirin; Naseri, Farkhondeh; Seirafian, Shiva

doi:10.1177/1129729820938216

Cited by 5 publications

(4 citation statements)

References 3 publications

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“…Foam dressings, honey dressings, hydrogel dressings, and silver ion dressings are the most commonly used dressings in clinical wound treatment [ 8 , 9 ]. Silver ion dressing on the ulcerated surface of diabetic foot can form a local antibacterial environment to reduce the chance of bacterial infection and, thus, reduce local secretion, with bactericidal and antibacterial effects and absorption of wound exudate [ 10 , 11 ]. Prontosan gel has a long-lasting preventive effect against bacterial biofilm, provides moisture to the wound, and can cause autolysis of necrotic tissue in the DF to promote wound healing [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Clinical Study on the Efficacy of Silver Ion Dressing Combined with Prontosan Gel Dressing in the Treatment of Diabetic Foot Ulcers and the Effect on Serum Inflammatory Factors

Chu

Tao

2021

Evidence-Based Complementary and Alternative Medicine

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Diabetic foot ulcers (DFUs) have a high disability rate and have a great impact on patients and society, and the search for effective and economical treatment options is a major clinical concern. In this study, 112 patients with DFU admitted to two hospitals from October 2018 to November 2020 were randomly divided into 56 cases each in the single group treated with Prontosan gel dressing and the joint group treated on silver ion dressing combined with Prontosan gel dressing. Both groups of patients were evaluated for efficacy after 30 days of treatment. The number of days for debridement, granulation tissue growth time, epithelial tissue formation time, and wound healing time were observed and recorded in both groups. The trauma area, visual analogue score (VAS), and levels of inflammatory factors such as vascular endothelial adhesion molecule-1 (VCAM-1), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and C-reactive protein (CRP) were recorded before and after treatment in both groups. The occurrence of adverse reactions such as edema, fever, infection, and rash during treatment was recorded in both groups for safety assessment. Comparison of the abovementioned data showed that the clinical efficacy of the joint group was significantly higher than that of the single group. The number of days to clear wounds, granulation tissue growth time, epithelial tissue formation time, and wound healing time were significantly lower in the joint group than in the single group. The trauma area, VAS score, VCAM-1, IL-6, TNF-α, and CRP levels decreased in both groups after treatment compared with the pretreatment levels, with the joint group being lower than the single group. The results also showed that the difference in the overall incidence of adverse reactions between the two groups was not statistically significant, and the incidence was low and transient. In addition to the usual treatment regimen of blood glucose control and improvement of microcirculation for patients with DFU, combined treatment with silver ionomer dressings and Prontosan gel dressings can promote ulcer healing and improve foot wound regression. It has a stronger antibacterial effect and can more effectively reduce the inflammatory response of the ulcerated surface with fewer adverse effects, making it an effective and safe method for the treatment of DFU, and has implications for promotion.

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Section: Introductionmentioning

confidence: 99%

Clinical Study on the Efficacy of Silver Ion Dressing Combined with Prontosan Gel Dressing in the Treatment of Diabetic Foot Ulcers and the Effect on Serum Inflammatory Factors

Chu

Tao

2021

Evidence-Based Complementary and Alternative Medicine

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“…Silver-containing dressings are composed of a 100% continuous nondeformable polyester fiber mesh hydrocolloid (sodium carboxymethylcellulose) and an antibacterial agent (silver ion complex). e mesh that is not easy to be deformed avoids the wound, can tolerate multiple mechanical stress effects, can be completely removed during dressing change, does not worry about dressing residues, and this dressing does not adhere to the wound and can significantly reduce pain [14,15]. e dressing has a mesh which is not easy to deform, does not adhere to the wound, and can obviously relieve pain; and it can withstand mechanical stress for many times, which can be completely taken out during dressing change without leaving dressing [16][17][18].…”

Section: Discussionmentioning

confidence: 99%

Application Effect of Silver-Containing Dressings in the Repair of Chronic Refractory Wounds

Wang

Guo

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Chronic refractory wounds have complicated pathogenesis, repeatedly prolonged course of disease, high difficulty in cure, and may even endanger life due to the spread of wound infection. Silver ion dressing is a new type of dressing applied clinically in recent years. It can prevent infection and promote wound healing by releasing a low level of active silver ions into wound fluid or secretion. Some scholars have found that silver ion dressings can promote the healing of refractory wounds. In this study, 80 cases of chronic refractory wounds treated in our department from June 2019 to January 2022 were selected as the research subjects and the effect of silver ion dressing coverage on the repair of chronic refractory wounds after debridement was explored.

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“…Treatment options include silver nitrate cauterisation, 88 topical chlorhexidine application 88 and silver ion-based dressing. 89 Although silver nitrate cauterisation has been most commonly used, this chemical agent can cause skin burns and pain. A small RCT involving 44 participants showed that chlorhexidine swab stick had similar efficacy of healing rate when compared to silver nitrate but had lower pain scores and less adverse reactions (burning sensation and staining around the exit site).…”

Section: Management Of Catheter-related Infectionsmentioning

confidence: 99%

ISPD Catheter-related Infection Recommendations: 2023 Update

Chow

Cho

et al. 2023

Perit Dial Int

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Peritoneal dialysis (PD) catheter-related infections are important risk factors for catheter loss and peritonitis. The 2023 updated recommendations have revised and clarified definitions and classifications of exit site infection and tunnel infection. A new target for the overall exit site infection rate should be no more than 0.40 episodes per year at risk. The recommendation about topical antibiotic cream or ointment to catheter exit site has been downgraded. New recommendations include clarified suggestion of exit site dressing cover and updated antibiotic treatment duration with emphasis on early clinical monitoring to ascertain duration of therapy. In addition to catheter removal and reinsertion, other catheter interventions including external cuff removal or shaving, and exit site relocation are suggested.

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Successful treatment of peritoneal dialysis catheter exit-site granuloma with silver ion-based dressing

Cited by 5 publications

References 3 publications

Clinical Study on the Efficacy of Silver Ion Dressing Combined with Prontosan Gel Dressing in the Treatment of Diabetic Foot Ulcers and the Effect on Serum Inflammatory Factors

Clinical Study on the Efficacy of Silver Ion Dressing Combined with Prontosan Gel Dressing in the Treatment of Diabetic Foot Ulcers and the Effect on Serum Inflammatory Factors

Application Effect of Silver-Containing Dressings in the Repair of Chronic Refractory Wounds

ISPD Catheter-related Infection Recommendations: 2023 Update

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